… the development of sepsis if we are to optimize these present clinical therapies and/or develop
… , developing evidence in sepsis research suggests that increased apoptosis may play a …

… Several lines of evidence have supported the feasibility of developing TSN-SS as potential
therapies for human sepsis. These include the lack of drug toxicity in the clinical management …

… Therefore, since MDSCs may be therapeutic target cells for sepsis-induced … CTLA-4
antibody treatment attenuates sepsis-induced apoptosis and improves survival in a …

… Several studies have highlighted the extensive apoptosis of immune cells during acute
sepsis as a prominent driver of subsequent immune dysfunction. Besides a depletion in sheer …

… therapies for sepsis. Fundamental questions regarding the cellular pathogenesis of experimental
and clinical sepsis … pathway and apoptosis represent promising new therapeutic options…

… of renal injury during sepsis and propose how changes in the … We also discuss a number
of potential therapeutic targets in the … many of the therapeutic targets discussed in this review. …

… therapeutic target for drug abuse [38] and major depressive disorders [39,40] , as well as
amyotrophic lateral sclerosis [41]. Possible … showed that attenuation of apoptotic depletion of T …

… infection to eventual sepsis and a potential combined therapeutic strategy for targeting
sepsis… Bcl-2 is an anti-apoptosis protein and is found to be reduced in sepsis (56). …

… therapeutic approaches targeting different immunological mechanisms in the course of sepsis
and septic shock, … Apart from sepsis-induced lymphopenia, an increased rate of apoptosis …

… One of the most notable T cell defects induced by sepsis is the development of apoptosis, …
IL-3 as a potential therapeutic target in sepsis (101). Potential immune-modulatory therapies …