… , as predominant causes of mortality in sepsis patients. This understanding of sepsis-induced
organ failure unveils potential therapeutic targets for sepsis treatment. Various novel …

… for newer therapeutic targets in sepsis is still on and miRNAs could be the potential targets.
… to prevent apoptosis and organ damage in sepsis [168, 169]. The inhibition of miR-195 in …

… may be related to IL-2 suppression, another characteristic of both MODS and sepsis (40) . …
apoptosis during sepsis as well. In a CLP murine model of sepsis, bone marrow cell apoptosis …

… Such information will surely provide not only new insight into the pathobiology of sepsis,
but also better therapeutic targets for the management of this devastating condition. …

… the crucial role that microcirculation plays in sepsis. If not corrected, … as an important target
in the pathogenesis of sepsis and its … diagnostic and therapeutic target for treatment in sepsis. …

… might represent an important step in the apoptotic loss of lymphocytes during sepsis. Taken
together, these studies indicate that caspase-3 is a potential therapeutic target in sepsis. …

… Similar scientific research, focused on the apoptotic/anti-apoptotic and oxidant/antioxidant
pathways in sepsis, might reveal promising therapeutic targets and encourage novel …

… sepsis cascade including inflammatory cytokines, cellular receptors, nuclear transcription
factors, coagulation activators and apoptosis … of sepsis, has been a central therapeutic target …

… M-791 decreased lymphocyte apoptosis in thymus and spleen of mice subjected to sepsis
induced by cecal ligation-puncture and rescued 80–90% of animals from lethal septic shock. …

… of S-AKI may lead to the development of therapeutic targets. … It is also possible that LMP
and CTSB may prevent S-AKI … triggered apoptosis through mitochondrial apoptosis pathway in …