… We hope the discussion of such studies provides not only new insight into the pathobiology
of sepsis, but also suggests possible therapeutic targets for the management of this …

… in the exploration of therapeutic targets for the discovery of drugs … therapeutic targets and
to investigate the characteristics of these targets for providing useful clues to search new targets…

… Epigenetic abnormalities in cancer have an important biological and clinical impact. An
increasing body of research provides evidence that aberrant epigenetic mechanisms affect the …

… The FDA approval of 1st generation epigenetic therapies highlights the validity of the
epigenome as a therapeutic target. These 1st generation epigenetic therapies provide a clinical …

… Furthermore, we summarize potential therapeutic approaches targeting TLRs, their
endogenous ligands and the signaling pathways associated with these receptors (Fig. 2). …

… Inhibitors of apoptosis therefore remain a therapeutic target of interest for PD as well as for
other neurodegenerative disorders. To date, there has been no evidence that such agents …

… Apart from the absence of specific therapies, the lack of knowledge about potential
therapeutic targets and individual perception is adding to the complications. The present review …

… that the HDLs have multiple protective antiatherogenic functions that identify HDL cholesterol
and HDL metabolism as therapeutic targets for the prevention of CAD in patients at risk. …

… activation has also been examined as a potential therapeutic target in IBD. This has been
verified … has further validated SK1 inhibition as a potential therapeutic target in IBD. In the DSS-…

… 9), thus raising the possibility that ageing and longevity may be therapeutic targets for … PI3K
complex, is a potential target for drugs. Some other potential targets are also indicated on the …