Advances in drug development for hepatocellular carcinoma: clinical trials and potential therapeutic targets
XY Luo, KM Wu, XX He - … of Experimental & Clinical Cancer Research, 2021 - Springer
… atmosphere in the HCC drug research and development field… in clinical phase I/II/III trials
and identifies emerging targets for … potential problems in HCC drug therapy and possible future …
and identifies emerging targets for … potential problems in HCC drug therapy and possible future …
Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements
A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
… Apart from the absence of specific therapies, the lack of knowledge about potential
therapeutic targets and individual perception is adding to the complications. The present review …
therapeutic targets and individual perception is adding to the complications. The present review …
Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer
GH Li, JF Huang - Bioinformatics, 2014 - academic.oup.com
… drug or one being used in clinical trials. Further investigations indicate that HKDC1 is a novel
potential therapeutic target … to identify potential therapeutic targets from heterogeneous data…
potential therapeutic target … to identify potential therapeutic targets from heterogeneous data…
Therapeutic targets: progress of their exploration and investigation of their characteristics
… So far, most clinical trials of MMP inhibitors have not yielded good results, due primarily to
the lack of subtype selectivity, bioavailability, and efficacy and in some cases inappropriate …
the lack of subtype selectivity, bioavailability, and efficacy and in some cases inappropriate …
Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies
YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - … and targeted therapy, 2021 - nature.com
… COVID-19, the therapeutic targets and interventions of COVID-19 have been classified into
… target virus” and “target host” categories. A comprehensive analysis of the therapeutic targets …
… target virus” and “target host” categories. A comprehensive analysis of the therapeutic targets …
Neuroinflammation: a potential therapeutic target
JM Craft, DM Watterson, LJ Van Eldik - … on therapeutic targets, 2005 - Taylor & Francis
… Indeed, a small prospective clinical trial using atorvastatin showed some protective effects …
target neuroinflammation as a therapeutic target for neurodegenerative disease progression. …
target neuroinflammation as a therapeutic target for neurodegenerative disease progression. …
Potential Therapeutic Strategies for Alzheimer's Disease Targeting or Beyond β‐Amyloid: Insights from Clinical Trials
Q Jia, Y Deng, H Qing - BioMed research international, 2014 - Wiley Online Library
… better therapy an urgent issue. Here we attempt to summarize and compare putative therapeutic
strategies that have completed clinical trials … can be potential therapeutic targets for drug …
strategies that have completed clinical trials … can be potential therapeutic targets for drug …
PI3K: a potential therapeutic target for cancer
Y Chen, BC Wang, Y Xiao - Journal of cellular physiology, 2012 - Wiley Online Library
… cancer potential therapeutic agents. As competitive ATP binders, LY294002 and wortmannin
are revealed to be the vast potential … coming into clinical trials, therapeutic potential of PI3K …
are revealed to be the vast potential … coming into clinical trials, therapeutic potential of PI3K …
Apoptosis: potential therapeutic targets for new drug discovery
S Jana, J Paliwal - Current medicinal chemistry, 2007 - ingentaconnect.com
… tailor-made therapies that will result in improved clinic. From … found in the preclinical and
clinical trials. The lack of specific … for a long time the clinical investigation of this target. But in the …
clinical trials. The lack of specific … for a long time the clinical investigation of this target. But in the …
Epigenetic changes: potential therapeutic targets
T Kalebic - Annals of the New York Academy of Sciences, 2003 - Wiley Online Library
… during tumorigenesis have been exploited as new targets for therapeutic intervention.
Clinical studies exploring the effectiveness of therapeutic agents targeting DNA methylation and …
Clinical studies exploring the effectiveness of therapeutic agents targeting DNA methylation and …
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