Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements

A Pandey, AN Nikam, AB Shreya, SP Mutalik… - Life sciences, 2020 - Elsevier
… However, it's likely to take months to years to develop new drug/vaccine associated … on the
drug repurposing techniques and the ability to repurpose current therapeutic agents for COVID…

Drug repurposing approaches: existing leads for novel threats and drug targets

T Usha, SK Middha, AA Kukanur… - Current Protein and …, 2021 - ingentaconnect.com
… of old anti-infective, anti-rheumatic and anti-thrombotic drugs. The goal of the current
review is to elaborate the process of DR, its advantages, repurposed drugs for a plethora of …

[HTML][HTML] Drug repurposing strategy (DRS): Emerging approach to identify potential therapeutics for treatment of novel coronavirus infection

BM Sahoo, BVV Ravi Kumar, J Sruti… - Frontiers in Molecular …, 2021 - frontiersin.org
… new drug candidates against the different therapeutic targets of … drugs have been repurposed
to identify possible therapeutic … , favipiravir and antimalarial drugs such as chloroquine, …

[HTML][HTML] Drug repurposing for COVID-19: A review and a novel strategy to identify new targets and potential drug candidates

L Rodrigues, R Bento Cunha, T Vassilevskaia… - Molecules, 2022 - mdpi.com
drug repurposing strategy to identify new anti-SARS-CoV-2 compounds that may be potentially
… any SARS-CoV-2 encoded protein may represent a valid and potential therapeutic target. …

Network-based approaches reveal potential therapeutic targets for host-directed antileishmanial therapy driving drug repurposing

JE Martinez-Hernandez, Z Hammoud… - Microbiology …, 2021 - Am Soc Microbiol
… identifies potential therapeutic targets in the host cell and proposes known drug interactions
… gene expression profiles, we selected potential therapeutic target proteins. The function of …

Drug Repurposing Approach, Potential Drugs, and Novel Drug Targets for COVID‐19 Treatment

ZD Kifle, AG Ayele, EF Enyew - Journal of Environmental and …, 2021 - Wiley Online Library
… that are summarized in this review primarily focused on therapeutic agents that … Drug
repurposing or repositioning is a promising field in drug discovery that identifies new therapeutic

[HTML][HTML] Computer-aided drug repurposing for cancer therapy: approaches and opportunities to challenge anticancer targets

C Mottini, F Napolitano, Z Li, X Gao… - Seminars in cancer biology, 2021 - Elsevier
… We will discuss how in-silico drug repurposing has the promise to … drugs and, likely,
overcome certain limitations of modern cancer therapies against old and new therapeutic targets in …

Drug repurposing approach to combating coronavirus: Potential drugs and drug targets

J Xu, Y Xue, R Zhou, PY Shi, H Li… - Medicinal research …, 2021 - Wiley Online Library
… is a rapid and feasible strategy to identify effective drugs for combating this … therapeutic
CoV targets, focus on the existing small molecule drugs that have the potential to be repurposed

Drug repurposing: far beyond new targets for old drugs

TI Oprea, J Mestres - The AAPS journal, 2012 - Springer
therapeutic applications. This is normally being referred to as drug repurposing [9] or repositioning
… academia to assume that drug repurposing is just about identifying new targets for old …

[HTML][HTML] Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance

D Ajmeera, R Ajumeera - Genes & Diseases, 2024 - Elsevier
… Further, drug repurposing and the combination of micronutrients that can target both … such
as NF-κB, HIF-1α, and β-catenin were also considered therapeutic targets to eradicate CSCs. …