过去一年中添加的文章,按日期排序

[HTML][HTML] Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer

X Tian, G Liu, L Ji, Y Shen, J Gu, L Wang, J Ma… - Translational …, 2025 - Elsevier
2 天前 - … however, the comprehensive epigenetic landscape that functionally … to investigate
epigenetic modifications for histones in … and potential therapeutic target for treatment in CRC. …

Study of RNA biology and splicing in pancreatic cancer and neuroendocrine tumors

R Blázquez Encinas-Rey - 2024 - helvia.uco.es
3 天前 - … , highlighting the role of epigenetic changes and alterations in gene expression.
Recent … understand tumor complexity and identify new therapeutic targets, paving the way for …

The effect of methylation on the let-7-BCL2L1-BCL2 axis and the potential use of hypomethylating and BH3 mimetic drugs in histiocytic neoplasms

M Salmon-Divon, R Meyuchas, O Shpilberg, E Okon… - Leukemia, 2024 - nature.com
3 天前 - Epigenetic changes are potentially reversible by … providing a promising target
for therapeutic intervention. … Therefore, identifying new therapeutic targets is needed …

[HTML][HTML] Epigenetics in Heart Failure

JSY Ho, E Jou, PL Khong, RSY Foo… - International Journal of …, 2024 - mdpi.com
4 天前 - … the potential epigenetic therapies currently in development, including the limited
clinical trials of epigenetic therapies … Therefore, DNMT may be potential therapeutic targets that …

MicroRNA-146 Family: Molecular insights into their role in regulation of signaling pathways in glioma progression

S Mirzaei, F Ahangari, F Faramarzi… - … -Research and Practice, 2024 - Elsevier
5 天前 - Glioma is a highly lethal brain cancer in humans. Despite advancements in
treatment, the prognosis for patients remains unfavorable. Epigenetic factors, along with their …

Oxytocin receptor epigenetics: from biomarker to potential therapeutic target

HH Burris, LK White, R Waller, BH Chaiyachati - Pediatric Research, 2024 - nature.com
5 天前 - … review of the epigenetics of the … into possible oxytocin-related biomarkers in brain
development, as well as studies that have explored oxytocin as a possible therapeutic target

[HTML][HTML] Estimating the Number of Polygenic Diseases Among Six Mutually Exclusive Entities of Non-Tumors and Cancer

CIE Smith, JA Burger, R Zain - International Journal of Molecular Sciences, 2024 - mdpi.com
5 天前 - … /epigenetic changes, recently named ‘Goners’, which are toxic for the neoplasm and
potentially constitute therapeutic targets… possibly also of epigenetic changes to the existing …

Role of reactive oxygen species in regulating epigenetic modifications

Y Chen, YQ Shen - Cellular Signalling, 2024 - Elsevier
5 天前 - epigenetic modifications to disease progression underscores their potential as crucial
therapeutic targets … This study begins by providing an overview of ROS and epigenetics, …

From Modification Maps to Clinical Impact: RNA Epigenetics in Cancer Diagnosis and Treatment

O Sweef, M Asfar, ES Choi, YL Corcino, VD Thomas… - 2024 - Springer
5 天前 - … RNA modifications also unveil a trove of therapeutic targets … for installing or erasing
specific modifications emerges as a … of individual RNA modifications within various cellular …

New Emerging Therapeutic Strategies Based on Manipulation of the Redox Regulation Against Therapy Resistance in Cancer

A Nazari, P Osati, S Seifollahy Fakhr… - Antioxidants & Redox …, 2024 - liebertpub.com
6 天前 - … be influenced by epigenetic mechanisms, which involve modifications to the structure
of … that redox regulation holds significant potential as a therapeutic target in the context of …