… in sepsis can control pathogen infection, excessive pyroptosis can lead to a dysregulated …
overview of the mechanisms and potential therapeutic targets underlying pyroptosis in sepsis …

… -independent pathway, are also described. We highlight the recent advances in pyroptosis
in … its potential advantages as a therapeutic target or prognostic marker in these diseases. …

… pharmaceutical agents that target a critical component of inflammasome activation, signaling
leading to cellular pyroptosis, and the downstream cytokines as a promising target for the …

… and pathophysiological mechanisms of the pyroptosis-related inflammasomes pathway in
the … new insights for researchers regarding the development of potential therapies for DCM. …

… pyroptotic signalling pathway is of great interest. In this review, we will address the pathogenic
role of pyroptosis in … the current therapeutic strategies that target pyroptotic proteins and …

… the mechanisms of pyroptosis and its role as a potential therapeutic target for I/R injury. …
This section discusses the role of pyroptosis in I/R injury in different organs and possible …

… Here, we focus on the molecular mechanisms of NLRP3 inflammasome in the pyroptosis
signaling pathway, including its prime, activation, and post-translational modifications. Moreover…

… membrane activating pyroptosis and apoptosis. We also discuss the potentiality of pyroptosis
as a therapeutic target in human diseases. Blockade of pyroptosis by compounds can treat …

… In terms of molecular mechanisms, the pyroptosis mechanism can be divided into two
pathways, namely, the canonical pathway mediated by caspase-1 and GSDMD, and the non-…

… be considered as a potential therapeutic approach to improve symptoms in HD patients [66]. …
of the pyroptotic pathway can play a certain protective role, providing potential targets for …