Toll-like receptors as potential therapeutic targets for multiple diseases

C Zuany-Amorim, J Hastewell, C Walker - Nature Reviews Drug …, 2002 - nature.com
… However, in addition to the potential therapeutic effect of blocking TLRs in sepsis, these … to
design therapeutics for the treatment of chronic inflammatory diseases or human diseases that …

Autophagy modulation as a potential therapeutic target for diverse diseases

DC Rubinsztein, P Codogno, B Levine - Nature reviews Drug discovery, 2012 - nature.com
… 9), thus raising the possibility that ageing and longevity may be therapeutic targets for … of
autophagy in various key diseases and review emerging strategies for therapeutic intervention. …

NMDARs in neurological diseases: a potential therapeutic target

J Gonzalez, JC Jurado-Coronel, MF Avila… - International Journal …, 2015 - Taylor & Francis
disease (PD) and Huntington's disease to acute ischemia, trauma and epilepsy. Within the
neurologic disease states, … In this concern, we discuss some potential therapeutic strategies …

NF-κB, a potential therapeutic target for the treatment of multiple sclerosis

J Yan, JM Greer - … drug Targets-CNS & neurological Disorders), 2008 - ingentaconnect.com
… MS is generally considered to be an autoimmune disease directed … , as with many other
human chronic autoimmune diseases, the … and, thus, potential as a therapeutic target in MS. …

Adenosine and its receptors: multiple modulatory functions and potential therapeutic targets for neurologic disease

EE Benarroch - Neurology, 2008 - AAN Enterprises
… 9 Parkinson disease (PD), 8,14 and Huntington disease. There are several excellent reviews
… the CNS, 1–6,8 and on adenosine as a potential therapeutic target in neurologic disorders. …

Protein kinase CK2: a potential therapeutic target for diverse human diseases

C Borgo, C D'Amore, S Sarno, M Salvi… - … and targeted therapy, 2021 - nature.com
… the phosphorylation of several CK2 substrates (either viral and host proteins). CK2 is also
considered an emerging target for neurological diseases, inflammation and autoimmune …

IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases

RX Leng, HF Pan, JH Tao, DQ Ye - … opinion on therapeutic targets, 2011 - Taylor & Francis
… These data indicate that IL-20R2 may be a novel therapeutic target, and furthermore, support
the hypothesis that IL-19 and IL-24 possessed redundant function in this model Citation[37]…

Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
… Another method of microbiota manipulation of increasing interest for potential therapeutic
applications in various diseases is fecal microbiota transplantation (FMT). Recently, …

NF-κB, A potential therapeutic target in cardiovascular diseases

W Cheng, C Cui, G Liu, C Ye, F Shao… - … Drugs and Therapy, 2023 - Springer
… Thus, NF-κB is a potential therapeutic target in the treatment of atherosclerosis and related
CVDs. Several biologics and small molecules as well as peptide/proteins have been shown …

MicroRNAs: a novel class of potential therapeutic targets for cardiovascular diseases

Z Pan, Y Lu, B Yang - Acta Pharmacologica Sinica, 2010 - nature.com
… These results indicate that miRNAs are important regulators in the development of
proliferative vascular diseases and the potential therapeutic targets in vascular diseases. …