… As these roles become clearer, new therapeutic targets are being identified … sphingolipid
mediators in the inflammatory process and highlight exciting directions for novel therapeutic …

… sphingolipids as regulators and mediators of cytokines and associated mucosal immunity
and inflammation … sphingolipid impact on IBD development and treatment, currently available …

… of the expression of various inflammatory mediators and regulation of … sphingolipids and
AD have suggested that sphingolipids, … AD biomarkers as well as potential therapeutic targets. …

… This is followed by an anti-inflammatory phase, in which resident tissue cells may acquire
the potential for protecting themselves from further activation and injury. Inflammation is now …

… how sphingolipids are implicated in the progression of atherosclerosis and related diseases,
and then we discuss the potential therapy … Sphingolipid metabolites in inflammatory disease …

… and SphK2) produces S1P, a crucial metabolite and intermediate in the sphingolipid pathway
[17]. S1P is an anti-inflammatory, pro-proliferative, and anti-apoptotic signaling molecule. …

… of the sphingolipidmediated … which sphingolipids induce inflammatory responses via the
eicosanoid pathway in addition to linking previous literature on sphingolipids and inflammation …

… of sphingolipids in the regulation of cancer cell death and tumor development. It also
provides an update on the potential perspectives of manipulating sphingolipid … inflammatory …

… sphingolipid signal transduction pathways has helped to identify potential new therapeutic
targets … kinases are indeed novel targets for the modulation of inflammatory conditions, we …

… Several studies now showed that these sphingolipid mediators and their enzymes, …
proliferation, inflammation, apoptosis and migration. The mode of action of each sphingolipid is …