… Stimulation of peroxisome proliferator-activated receptor alpha (PPAR alpha) attenuates
cardiac fibrosis and Endothelin-1 production in pressure-overload rat hearts. Clin Sci (Lond) …

… diabetes mellitus, cardiovascular disease remains the leading … The PPAR family, including
PPAR-alpha, play important … Fibrates act upon PPAR-alpha and appear to target the typical …

… in the various cardiovascular diseases and summarize … PPAR alpha and γ activators are
being developed to combine the HDL-C raising and triglyceride lowering effect of PPAR alpha …

… Cardiovascular disease is the leading cause of morbidity and mortality world-wide. The burden
of disease is also … Experimental evidence shows that the PPARs play a central role in the …

… In spite of the recent advances in the prevention and treatment of cardiovascular disease
(CVD), it still remains the leading cause of death globally, accounting for 17.3 million deaths …

… , nonalcoholic fatty liver disease and cardiovascular disease. The aim … and metabolic actions
of PPAR-β/δ and PPAR-γ, the … the cardiovascular disease outcome of clinical trials of PPAR-…

… disease defined by hyperglycaemia; however, strong associations with abdominal obesity,
hypertension and dyslipidaemia contribute to the high risk of cardiovascular disease. … (PPAR) …

… cardiovascular diseases. Accumulating evidence has shown that the three PPAR subtypes
function in the cardiovascular … R: Activation of PPAR alpha by fenofibrate inhibits apoptosis in …

… cardiovascular disease (CVD). The metabolic syndrome is characterized by central obesity,
elevated blood pressure, insulin resistance, impaired glucose tolerance or diabetes mellitus …

… of cardiovascular disease (CVD). Peroxisome proliferator-activated receptors (PPARs), one
of … This review discusses the role of PPARs and their ligands in the cardiac myocytes energy …