Radiomics as a quantitative imaging biomarker: practical considerations and the current standpoint in neuro-oncologic studies

JE Park, HS Kim - Nuclear medicine and molecular imaging, 2018 - Springer
… and practical considerationsimaging, basic radiomics workflow, illustrating examples of
the promise in neuro-oncology research, and future consideration as a new imaging biomarker

Methods and challenges in quantitative imaging biomarker development

RG Abramson, KR Burton, JY John-Paul, EM Scalzetti… - Academic radiology, 2015 - Elsevier
radiology is poised to play an important role in the development and implementation of
quantitative imaging … evaluation of QI biomarker utilization also addresses practical issues around …

Statistical considerations for planning clinical trials with quantitative imaging biomarkers

NA Obuchowski, PD Mozley, D Matthews… - JNCI: Journal of the …, 2019 - academic.oup.com
… in new drug development and clinical practice. Quantitative imaging biomarkers (QIBs) are
… Although quantitative measurements can have many advantages compared with subjective, …

Quantitative imaging biomarkers in the clinical development of targeted therapeutics: current and future perspectives

JPB O'Connor, A Jackson, MC Asselin… - The lancet …, 2008 - thelancet.com
… Here, we review current quantitative imaging biomarkers that can be … imaging biomarkers
that are in preclinical and early clinical use. We emphasise important practical considerations

Quantitative imaging as cancer biomarker

DA Mankoff - … Imaging 2015: Physics of Medical Imaging, 2015 - spiedigitallibrary.org
… This review highlights use of molecular imaging as a cancer biomarker to direct targeted …
cancer imaging biomarkers could be an important part of clinical trials and clinical practice, …

Metrology standards for quantitative imaging biomarkers

DC Sullivan, NA Obuchowski, LG Kessler, DL Raunig… - Radiology, 2015 - pubs.rsna.org
… The term quantitative imaging has been defined as “the extraction of quantifiable features …
two concepts of biomarkers and quantitative imaging, a quantitative imaging biomarker ( QIB ) …

Quantitative imaging biomarkers: a review of statistical methods for technical performance assessment

DL Raunig, LM McShane, G Pennello… - … methods in medical …, 2015 - journals.sagepub.com
… used to assess a quantitative imaging biomarker for clinical use… America and the Quantitative
Imaging Biomarker Alliance with … evaluation of quantitative imaging biomarker performance …

Quantitative imaging test approval and biomarker qualification: interrelated but distinct activities

AJ Buckler, L Bresolin, NR Dunnick, DC Sullivan… - Radiology, 2011 - pubs.rsna.org
… validation, and qualification of quantitative imaging biomarkers and to propose … quantitative
imaging biomarkers. A flexible framework is described that may be adapted for each imaging

The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions

LG Kessler, HX Barnhart, AJ Buckler… - … methods in medical …, 2015 - journals.sagepub.com
… research studies and quantitative imaging biomarker claims that … use of quantitative imaging
biomarker terminological … reviewers who examine quantitative imaging biomarkers and will …

Importance of incorporating quantitative imaging biomarker technical performance characteristics when estimating treatment effects

NA Obuchowski, EM Remer, K Sakaie… - Clinical …, 2021 - journals.sagepub.com
Quantitative imaging biomarkers have the potential to detect change in disease early and …
the variability and bias in quantitative imaging biomarker measurements. Unfortunately, this …