… a practice guideline [3]. PubMed and Internet searches were performed using the following
terms: “intrahepatic cholestasis of pregnancy”, “obstetric cholestasis”, “cholestasis of …

… Practice Guidelines (CPG) on the management of cholestatic … in the management of patients
with cholestatic liver diseases. They … Intrahepatic cholestasis may result from hepatocellular …

… Gestational cholestasis constitutes a classic example of intrahepatic cholestasis. The etiology
of … Cholestasis increases the risk of premature labor, presence of meconium in the amniotic …

… liver disease can be subdivided into different types according to its clinical phenotype, such
as biliary atresia, drug-induced cholestasis, gallstone liver disease, intrahepatic cholestasis …

… This guideline summarises the evidence regarding the diagnosis, and the maternal and fetal
risks of intrahepatic cholestasis of pregnancy (ICP), previously called obstetric cholestasis. …

… controlled trials to support or refute this practice. Of note, oral vitamin K substitution seems
to be counterintuitive in cholestasis and oral preparations have been removed from the …

… Clinical studies evaluating novel agents with antipruritic and disease-modifying properties
and updated clinical practice guidelines are needed. Based on the most recent evidence, …

… not have a guideline on the management of intrahepatic cholestasis of … guideline for
intrahepatic cholestasis of pregnancy states that there is no evidence to support or refute this practice…

… national guidelines for the management of intrahepatic cholestasis … practice have found
that 97% of obstetricians in the UK use ursodeoxycholic acid for treating intrahepatic cholestasis …

… Synthesis, including recent larger trials, will provide more evidence to guide clinical
practice. This review is an update of a review first published in 2001 and last updated in 2013. …