Peroxiredoxin 2 nuclear levels are regulated by circadian clock synchronization in human keratinocytes

D Avitabile, D Ranieri, A Nicolussi, S D'Inzeo… - … International Journal of …, 2014 - Elsevier
… Nuclear levels of the antioxidant enzyme Peroxiredoxin 2 (PRDX2) were found to
oscillate rhythmically over two entire 24 h long cycles. Donwregulation of PRDX2 resulted in …

Clock protein Bmal1 and Nrf2 cooperatively control aging or oxidative response and redox homeostasis by regulating rhythmic expression of Prdx6

B Chhunchha, E Kubo, DP Singh - Cells, 2020 - mdpi.com
clock, and its depletion leads to ablation of biological rhythm [6,7]. The master circadian
clock is … Prdx 1 to 5 contains 2-Cys Prdx, while Prdx6 has a single conserved Cys. Prdx6 is …

Mitochondrial H2O2 signaling is controlled by the concerted action of peroxiredoxin III and sulfiredoxin: linking mitochondrial function to circadian rhythm

SG Rhee, IS Kil - Free Radical Biology and Medicine, 2016 - Elsevier
… the circadian rhythm of H 2 O 2 release. … –SO 2 H) is reduced and reactivated by sulfiredoxin
(Srx). We also found that the amounts of PrxIII–SO 2 H and Srx undergo antiphasic circadian

Peroxiredoxins are conserved markers of circadian rhythms

RS Edgar, EW Green, Y Zhao, G Van Ooijen… - Nature, 2012 - nature.com
… Here we show that oxidation–reduction cycles of peroxiredoxin proteins constitute a universal
marker for circadian rhythms in all domains of life, by characterizing their oscillations in a …

[HTML][HTML] Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and …

A Feliciano, F Vaz, VM Torres… - … et Biophysica Acta (BBA …, 2017 - Elsevier
… -Cys PRDXs has been seem as an evolutionary adapted mechanisms to allow H 2 O 2 -dependent
cell signaling purposes, circadian rhythm to PRDXs recycling/function and …

Circadian clocks in the hematologic system

D Pritchett, AB Reddy - Journal of biological rhythms, 2015 - journals.sagepub.com
… , circadian rhythms in these cells testify to the existence of a nontranscriptional circadian
clock… The catalytic cysteine of peroxiredoxin (PRX) can be oxidized to a sulfenic acid form (PRX-…

Circadian rhythm of hyperoxidized peroxiredoxin II is determined by hemoglobin autoxidation and the 20S proteasome in red blood cells

CS Cho, HJ Yoon, JY Kim, HA Woo… - Proceedings of the …, 2014 - National Acad Sciences
… By trial and error, we found that the circadian rhythm of Prx hyperoxidation could be monitored
for 48 h by maintenance of mouse RBCs in a modified version of DMEM. Experimental …

Circadian control of mitochondria in reactive oxygen species homeostasis

V Mezhnina, OP Ebeigbe, A Poe… - Antioxidants & redox …, 2022 - liebertpub.com
… the circadian clock and rhythms in mitochondria on ROS homeostasis. The circadian clock
… and they are linked with rhythmic oxidation/reduction of peroxiredoxin (PRDX) proteins (30). …

Early developmental nanoplastics exposure disturbs circadian rhythms associated with stress resistance decline and modulated by DAF-16 and PRDX-2 in C. elegans

CW Yu, YC Wu, VHC Liao - Journal of Hazardous Materials, 2022 - Elsevier
… We also hypothesized that circadian interference results in increased NPs … peroxiredoxin-2
(PRDX-2) is involved. Furthermore, we hypothesized that the NPs-induced circadian rhythms

[HTML][HTML] Molecular mechanisms of the circadian clockwork in mammals

I Robinson, AB Reddy - FEBS letters, 2014 - Elsevier
… oscillations in redox reactions link circadian rhythms to metabolic processes, and … circadian
rhythms. To assess this, oscillation in redox state of PRDX was used as a marker of circadian