… Notably the general process of copper(II) binding by this type of molecular scaffold implies
the progressive engagement of peptide nitrogen in metal coordination. However, the nature of …

… The bioassays implied that comparing to the PAK peptides themselves and CuCl 2 the
coordination … Thus Cu(II)−peptide coordination indeed is a way for thrombolytic peptide design. …

… Upon addition of one molar equivalent of Cu(II) to a buffered solution of the Aβ 4–16 peptide,
we observe … Precise determination of the number of explicit waters to include in the primary …

… environments with precisely positioned amino acid … peptide binds DPP−Fe via bis(His)
coordination to low-spin Fe(III) and with a peptide/cofactor stoichiometry consistent with the design…

… coordination geometry as well as the oligomeric structure of the amphiphilic heptapeptide
in a designed … residues in each peptide adopt singly Nδ1-coordinated and doubly Nδ1, Nε2-…

… coordination sphere that can introduce the precise positioning reminiscent of enzymes.
Ultimately, this should allow us to understand precisely … peptide in the outer coordination sphere ([…

… to design of biologically inspired molecular catalysts that are intended to emulate the precise
… In addition to the influence of the second and outer coordination spheres in molecular and …

… can be used to mimic enzyme active sites because they can be designed as precise …
group reported the de novo design of a tris-His coordinated artificial Cu peptide (ArCuP), [3SCC-(I9H…

… model to mimic enzyme activity more precisely. The design of small peptides (SPs) and their
… the metal ion in the primary coordination sphere and the peptide residues involved in the …

… Nanoparticles (NPs) based on peptides and designed using … However, shortcomings in our
understanding of peptide self-… In this review, we discuss recent work in engineering peptide …