Base editing: precision chemistry on the genome and transcriptome of living cells

HA Rees, DR Liu - Nature reviews genetics, 2018 - nature.com
… Base editing is a newer genome-editing approach that … precise point mutations in genomic
DNA and RNA, highlight recent developments that expand the scope, specificity, precision

Publisher Correction: Base editing: precision chemistry on the genome and transcriptome of living cells.

HA Rees, DR Liu - Nature Reviews. Genetics, 2018 - europepmc.org
The originally published article contained errors in reference numbering throughout table 1 (DNA
base editors and their approximate editing windows) due to the unintended …

Implementation of whole-genome and transcriptome sequencing into clinical cancer care

E Cuppen, O Elemento, R Rosenquist, S Nikic… - JCO Precision …, 2022 - ascopubs.org
… How can whole-genome transcriptome sequencing (WGTS) be integrated into health care
systems to replace the standard of care for oncology? A panel of 25 global experts in oncology…

[HTML][HTML] International standards for genomes, transcriptomes, and metagenomes

CE Mason, E Afshinnekoo, S Tighe, S Wu… - Journal of Biomolecular …, 2017 - ncbi.nlm.nih.gov
… in genomics, including whole genomes, transcriptomes, mixed genomic samples (… ,
which will be essential for robust approaches in clinical genomics and precision medicine. …

[PDF][PDF] Applications and potentials of nanopore sequencing in the (epi) genome and (epi) transcriptome era

S Xie, AWS Leung, Z Zheng, D Zhang, C Xiao, R Luo… - The Innovation, 2021 - cell.com
The Human Genome Project opened an era of (epi)genomic research, and also provided a
platform for the development of new sequencing technologies. During and after the project, …

[HTML][HTML] A study protocol for validation and implementation of whole-genome and-transcriptome sequencing as a comprehensive precision diagnostic test in acute …

E Berglund, G Barbany, C Orsmark-Pietras… - Frontiers in …, 2022 - frontiersin.org
genomic information, have become the focal point of research interest as novel techniques
that can support precision … comprehensive genomic profiling for precision diagnostics. …

Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

C Manzoni, DA Kia, J Vandrovcova… - Briefings in …, 2018 - academic.oup.com
… systems and eventually the development of successful precision medicine. This review
cuts across the boundaries between genomics, transcriptomics and proteomics, summarizing …

The transcriptomic toolbox: resources for interpreting large gene expression data within a precision medicine context for metabolic disease atherosclerosis

C Marín de Evsikova, ID Raplee, J Lockhart… - Journal of Personalized …, 2019 - mdpi.com
… The ongoing NHLBI TOPmed (Trans-omics for precision medicine) effort to generate ~150,000
individual genomes’ sequences and ~50,000 transcriptomes for the most prevalent …

Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine

Y Hu, Z Wang, L Liu, J Zhu, D Zhang, M Xu… - Chemical …, 2021 - pubs.rsc.org
precision medicine involves more than peering at genomics data, which necessitates the
inclusion of other chemical … tyrosine kinase by integrated transcriptome and pTyr proteome …

Next-generation transcriptome assembly

JA Martin, Z Wang - Nature Reviews Genetics, 2011 - nature.com
… The accuracy and precision of gene expression counting are influenced by cDNA library …
When a reference genome for the target transcriptome is available, the transcriptome assembly …