Precision genome editing in the CRISPR era

J Salsman, G Dellaire - Biochemistry and cell biology, 2017 - cdnsciencepub.com
… With the introduction of precision genome editing using CRISPR–Cas9 technology, we
have entered a new era of genetic engineering and gene therapy. With RNA-guided …

Toward precision genome editing in crop plants

J Li, H Li, J Chen, L Yan, L Xia - Molecular Plant, 2020 - cell.com
precision genome editing in plants. Based on the recently developed prime editing strategy,
which enables gene … diverse strategies to achieve precise targeted gene/allele replacement …

Advances in crop breeding through precision genome editing

G Nerkar, S Devarumath, M Purankar, A Kumar… - Frontiers in …, 2022 - frontiersin.org
… HDR is less error prone compared to NHEJ and ensures precise modifications at the target
Precision genome editing can help in addressing these problems by generating plants with …

Precision genome editing: a small revolution for glycobiology

C Steentoft, EP Bennett, KTBG Schjoldager… - …, 2014 - academic.oup.com
… While different gene silencing strategies have had tremendous impact on many … -based
precision genome editing techniques enabling efficient and stable gene editing, including gene

Precision genome editing in the eye

S Suh, EH Choi, A Raguram, DR Liu… - Proceedings of the …, 2022 - National Acad Sciences
… introduced, base editing emerged in 2016 as a more precise genome editing technology that
… Combining these engineered AAVs with precision genome editing agents as the delivered …

Precision gene editing technology and applications in nephrology

Z WareJoncas, JM Campbell… - Nature Reviews …, 2018 - nature.com
… field of precision gene editing is empowering researchers to directly modify DNA. Gene editing
is … genomic sequences and an associated biochemical activity that serves as a functional …

Development of plant prime-editing systems for precise genome editing

R Xu, J Li, X Liu, T Shan, R Qin, P Wei - Plant Communications, 2020 - cell.com
… Prime-editing systems have the capability to perform efficient and precise genome editing
in human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test …

An update on precision genome editing by homology-directed repair in plants

J Chen, S Li, Y He, J Li, L Xia - Plant Physiology, 2022 - academic.oup.com
… At last, we discuss the existing challenges in precision genome editing by HDR and
propose future perspectives of HDR in plant biological science as well as crop improvement. …

Precision genome editing in plants: state-of-the-art in CRISPR/Cas9-based genome engineering

N Wada, R Ueta, Y Osakabe, K Osakabe - BMC Plant Biology, 2020 - Springer
… The CRISPR/Cas9 system has been developed for precise genome editing with minimal
effects on the genome by enhancing the specificity or avoiding the DSB [2, 3]. Furthermore, …

Development of CRISPR/Cas delivery systems for in vivo precision genome editing

Y Chen, Y Ping - Accounts of Chemical Research, 2023 - ACS Publications
… engineering, we provide our unique perspective on how genome editing can become
more precise by integrating both delivery materials and molecular switches for gene editors to …