Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine

Y Hu, Z Wang, L Liu, J Zhu, D Zhang, M Xu… - Chemical …, 2021 - pubs.rsc.org
… biomarker mapping can … chemical mapping and profiling, and a perspective on their clinical
utility to improve the molecular understanding of diseases for advancing precision medicine

A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application

M Garland, JJ Yim, M Bogyo - Cell chemical biology, 2016 - cell.com
… many of the precision therapeutics. In this way, imaging with optical guidance during surgery
represents a technology complementary to the aims of precision medicine in diagnostics …

Molecular networking as a drug discovery, drug metabolism, and precision medicine strategy

RA Quinn, LF Nothias, O Vining, M Meehan… - Trends in …, 2017 - cell.com
… data as a relational spectral network thereby mapping the chemistry that was detected in an
MS/… drug metabolism, clinical diagnostics, and emerging applications in precision medicine. …

Microfluidic epigenomic mapping technologies for precision medicine

C Deng, LB Naler, C Lu - Lab on a Chip, 2019 - pubs.rsc.org
map 5fC at the single-nucleotide level, traditional bisulfite conversion (5fC > T) is compared
to bisulfite sequencing where 5fC is chemically … Thus, the isolated genomic sequences map

Towards precision medicine

EA Ashley - Nature Reviews Genetics, 2016 - nature.com
There is great potential for genome sequencing to enhance patient care through improved
diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, …

[HTML][HTML] Exploring the interdisciplinary nature of precision medicine: network analysis and visualization

X Xu, J Hu, X Lyu, H Huang, X Cheng - JMIR Medical …, 2021 - medinform.jmir.org
… Based on Stirling's diversity index and the specialization index, we have drawn a 2-dimensional
map of the interdisciplinary distribution of precision medicine research for every year …

Metabolomics enables precision medicine:“a white paper, community perspective”

…, “Precision Medicine and Pharmacometabolomics Task … - Metabolomics, 2016 - Springer
… tool for precision medicine We anticipate that the narrow range of chemical analyses in …
Also metabolic profiles provide tools for mapping global effects of drugs on metabolism, and …

Engineering precision medicine

W Sun, J Lee, S Zhang, C Benyshek… - Advanced …, 2019 - Wiley Online Library
… of precision medicine where therapeutics can be advised by the genetic background of
individuals. For example, mapping … Progress in polymer chemistry has improved our control over …

Enabling technologies for personalized and precision medicine

D Ho, SR Quake, ERB McCabe, WJ Chng… - Trends in …, 2020 - cell.com
… In personalized medicine, which has been considered for some time, the patient is viewed
… some overlaps with precision medicine in execution, but unlike precision medicine does not …

Targeting protein methylation: from chemical tools to precision medicines

D Dilworth, D Barsyte-Lovejoy - Cellular and Molecular Life Sciences, 2019 - Springer
… led to the development of a potent and selective chemical probe for L3MBTL3, UNC1215
(K d = 120 nM) [141]. Mapping of protein–protein interactions by mass spectrometry in …