Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine
Y Hu, Z Wang, L Liu, J Zhu, D Zhang, M Xu… - Chemical …, 2021 - pubs.rsc.org
… biomarker mapping can … chemical mapping and profiling, and a perspective on their clinical
utility to improve the molecular understanding of diseases for advancing precision medicine…
utility to improve the molecular understanding of diseases for advancing precision medicine…
A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application
… many of the precision therapeutics. In this way, imaging with optical guidance during surgery
represents a technology complementary to the aims of precision medicine in diagnostics …
represents a technology complementary to the aims of precision medicine in diagnostics …
Molecular networking as a drug discovery, drug metabolism, and precision medicine strategy
… data as a relational spectral network thereby mapping the chemistry that was detected in an
MS/… drug metabolism, clinical diagnostics, and emerging applications in precision medicine. …
MS/… drug metabolism, clinical diagnostics, and emerging applications in precision medicine. …
Microfluidic epigenomic mapping technologies for precision medicine
… map 5fC at the single-nucleotide level, traditional bisulfite conversion (5fC > T) is compared
to bisulfite sequencing where 5fC is chemically … Thus, the isolated genomic sequences map …
to bisulfite sequencing where 5fC is chemically … Thus, the isolated genomic sequences map …
Towards precision medicine
EA Ashley - Nature Reviews Genetics, 2016 - nature.com
There is great potential for genome sequencing to enhance patient care through improved
diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, …
diagnostic sensitivity and more precise therapeutic targeting. To maximize this potential, …
[HTML][HTML] Exploring the interdisciplinary nature of precision medicine: network analysis and visualization
X Xu, J Hu, X Lyu, H Huang, X Cheng - JMIR Medical …, 2021 - medinform.jmir.org
… Based on Stirling's diversity index and the specialization index, we have drawn a 2-dimensional
map of the interdisciplinary distribution of precision medicine research for every year …
map of the interdisciplinary distribution of precision medicine research for every year …
Metabolomics enables precision medicine:“a white paper, community perspective”
…, “Precision Medicine and Pharmacometabolomics Task … - Metabolomics, 2016 - Springer
… tool for precision medicine We anticipate that the narrow range of chemical analyses in …
Also metabolic profiles provide tools for mapping global effects of drugs on metabolism, and …
Also metabolic profiles provide tools for mapping global effects of drugs on metabolism, and …
Engineering precision medicine
… of precision medicine where therapeutics can be advised by the genetic background of
individuals. For example, mapping … Progress in polymer chemistry has improved our control over …
individuals. For example, mapping … Progress in polymer chemistry has improved our control over …
Enabling technologies for personalized and precision medicine
… In personalized medicine, which has been considered for some time, the patient is viewed
… some overlaps with precision medicine in execution, but unlike precision medicine does not …
… some overlaps with precision medicine in execution, but unlike precision medicine does not …
Targeting protein methylation: from chemical tools to precision medicines
D Dilworth, D Barsyte-Lovejoy - Cellular and Molecular Life Sciences, 2019 - Springer
… led to the development of a potent and selective chemical probe for L3MBTL3, UNC1215
(K d = 120 nM) [141]. Mapping of protein–protein interactions by mass spectrometry in …
(K d = 120 nM) [141]. Mapping of protein–protein interactions by mass spectrometry in …
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