CRISPR-cas9: a powerful tool towards precision medicine in cancer treatment

H Xing, L Meng - Acta Pharmacologica Sinica, 2020 - nature.com
… are essential factors in precision medicine. In this review, we summarize the common
strategies used for CRISPR-cas9 screening and its application to precision medicine. We also …

[HTML][HTML] Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicine

M Khoshandam, H Soltaninejad, M Mousazadeh… - Genes & …, 2024 - Elsevier
CRISPR/Cas9 in various illnesses are described. Due to its high precision and efficiency,
CRISPR/Cas9CRISPR genome editing as a modern precision medicine for cancer treatment. …

CRISPRCas9: A cornerstone for the evolution of precision medicine

S Razzouk - Annals of Human Genetics, 2018 - Wiley Online Library
… It is the finest approach for precision medicine. Genome editing is a state-of-the-art … In
this report, we introduce one aspect of genome editing, the CRISPR/Cas9 system, highlight its …

[HTML][HTML] Applications of CRISPR-Cas9 for advancing precision medicine in oncology: from target discovery to disease modeling

M Ravichandran, D Maddalo - Frontiers in Genetics, 2023 - frontiersin.org
… In this review, we provide our perspectives on the recent advancements in CRISPR technology
and its impact on precision medicine, ranging from target identification, disease modeling…

CRISPR-Cas9 genome engineering: trends in medicine and health

S Zaib, MA Saleem, I Khan - Mini reviews in medicinal …, 2022 - ingentaconnect.com
… most versatile, reliable, and precise method of genetic manipulation, thus … CRISPR-Cas9
in the field of medical research. Compared with other gene-editing technologies, CRISPR/Cas9

[HTML][HTML] CRISPR based therapeutics: a new paradigm in cancer precision medicine

S Das, S Bano, P Kapse, GC Kundu - Molecular Cancer, 2022 - Springer
CRISPR-Cas elements should fuel greater application of the latter in the realm of precision
medicine. … The type II Cas9 system is regarded as the prototype of CRISPR-Cas systems. The …

CRISPR/Cas9‐mediated genome editing: From basic research to translational medicine

FV Jacinto, W Link, BI Ferreira - … and molecular medicine, 2020 - Wiley Online Library
… by CRISPR/Cas9 allows for precise genome editing through HDR in post-mitotic neurons
in mouse brain.153 Another challenge imposed by the need of correcting specific mutations …

[HTML][HTML] Precision cancer mouse models through genome editing with CRISPR-Cas9

H Mou, Z Kennedy, DG Anderson, H Yin, W Xue - Genome medicine, 2015 - Springer
… (CRISPR)-Cas9 system, a powerful genome-editing tool for efficient and precise genome …
Here, we review how CRISPR-Cas9 has been used to create germline and somatic mouse …

[HTML][HTML] CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer

SC Selvakumar, KA Preethi, K Ross, D Tusubira… - Molecular Cancer, 2022 - Springer
… Personalized or precision medicine combines genetic information with phenotypic and
environmental … Precision medicine is now possible thanks to cancer genome sequencing. Having …

[HTML][HTML] Precision medicine in the era of CRISPR-Cas9: evidence from Bosnia and Herzegovina

S Semiz, PC Aka - Palgrave Communications, 2019 - nature.com
… of precision medicine is the high … precision medicine, particularly genetic testing, genetic
counseling, and genome editing, in Bosnia and Herzegovina (BH), in the era of CRISPR-Cas9 […