[HTML][HTML] Personalized or precision medicine? The example of cystic fibrosis

FAL Marson, CS Bertuzzo, JD Ribeiro - Frontiers in pharmacology, 2017 - frontiersin.org
… However, more recently, the term precision medicine began to be … In precision medicine, we
understand the individual as a response … medicine and precision medicine based on the CF. …

Cystic fibrosis in the era of precision medicine

SM Paranjape, PJ Mogayzel Jr - Paediatric respiratory reviews, 2018 - Elsevier
Cystic fibrosis (CF), a complex disorder characterized by … Cystic fibrosis results from
mutations located on chromosome 7q31.2, which encodes a protein known as the cystic fibrosis

Cystic fibrosis–an example of personalized and precision medicine

M Skov, CR Hansen, T Pressler - Apmis, 2019 - Wiley Online Library
Cystic fibrosis (CF) is a severe, monogenic, autosomal recessive disease caused by mutations
in the CFTR (cystic fibrosis … a new era of precision medicine targeting the basic defect …

[HTML][HTML] CFTR modulators: the changing face of cystic fibrosis in the era of precision medicine

M Lopes-Pacheco - Frontiers in pharmacology, 2020 - frontiersin.org
Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF … the pipeline
of novel modulators that may result in effective precision medicine for all individuals with CF. …

[HTML][HTML] CFTR modulators: shedding light on precision medicine for cystic fibrosis

M Lopes-Pacheco - Frontiers in pharmacology, 2016 - frontiersin.org
… Pathophysiological cascade of respiratory disorder in cystic fibrosis – Cellular mechanism
of cystic fibrosis begins with the defective CFTR (cystic fibrosis transmembrane conductance …

Making precision medicine personal for cystic fibrosis

C Manfredi, JM Tindall, JS Hong, EJ Sorscher - Science, 2019 - science.org
… addressed by innovative and powerful approaches to promote CF precision medicine. …
clinical setting toward the objective of making precision medicine more personal, and less strictly …

[HTML][HTML] Recent progress in translational cystic fibrosis research using precision medicine strategies

DM Cholon, M Gentzsch - Journal of Cystic Fibrosis, 2018 - Elsevier
cystic fibrosis … in cystic fibrosis combined with relevant precision medicine models provide
a framework for identifying optimal and sustained treatments that will benefit all cystic fibrosis

Cystic fibrosis transmembrane conductance regulator modulators: precision medicine in cystic fibrosis

EB Burgener, RB Moss - Current opinion in pediatrics, 2018 - journals.lww.com
… Functional classification of cystic fibrosis transmembrane conductance regulator mutations
causing cystic fibrosis with major examples in each class, associated approach to targeted …

[HTML][HTML] Cystic fibrosis lung disease modifiers and their relevance in the new era of precision medicine

A Sepahzad, DJ Morris-Rosendahl, JC Davies - Genes, 2021 - mdpi.com
… of cystic fibrosis (CF) has grown exponentially since the discovery of the cystic fibrosis
modifier genes of lung disease in cystic fibrosis and considers the interaction between modifiers …

Precision medicine based on CFTR genotype for people with cystic fibrosis

I Haq, M Almulhem, S Soars, D Poulton… - … Personalized Medicine, 2022 - Taylor & Francis
Cystic fibrosis (CF) is an autosomal recessive genetic condition that is caused by variants in
the cystic fibrosis … This causes multisystem disease due to dysfunction of the cystic fibrosis