… ” interventions for specific abnormalities of the cystic fibrosis … with CF worldwide—barriers
to precision therapy remain. These … has occurred regarding CF precision medicine, this review …

… Cystic fibrosis (CF) is a severe, monogenic, autosomal recessive disease caused by
mutations in the CFTR (cystic fibrosis transmembrane regulator) gene, where disturbed chloride …

… in developing precision therapies for cystic fibrosis; however, highly effective treatments that
target … drug efficacy to support individualized treatment plans and translational research are …

… It was originally anticipated that well-established disease subclasses would serve as an
organizing principle for precision CF treatments and help identify specific compounds for …

… Cystic fibrosis (CF) is a lethal inherited disease caused by mutations in the CF … Mutations
in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause cystic fibrosis (…

… The treatment of people with cystic fibrosis (CF) has been … embodies the goals of precision
medicine, which incorporate … individualized ushering in a new era of precision medicine. …

… The genetic multisystem condition cystic fibrosis (CF) has seen a paradigm shift in … , treatment
advances had focused on the downstream consequences of a dysfunctional cystic fibrosis …

… of precision treatment for cystic fibrosis using small-molecule therapeutics has created a
need to estimate potential clinical improvements attributable to increases in cystic fibrosis …

… cystic fibrosis transmembrane conductance regulator gene. This causes multisystem disease
due to dysfunction of the cystic fibrosis … Until recently, treatment was directed at managing …

… Pathophysiological cascade of respiratory disorder in cystic fibrosis – Cellular mechanism
of cystic fibrosis begins with the defective CFTR (cystic fibrosis transmembrane conductance …