Sensitive and rapid bioassay for analysis of P-glycoprotein-inhibiting activity of chemosensitizers in patient serum.

M Lehnert, R de Giuli, PR Twentyman - … cancer research: an official journal of …, 1996 - AACR
… is whether the concentrations achieved by chemosensitizers … -inhibiting activity of
chemosensitizer-containing patient serum. … for monitoring chemosensitizer treatment in cancer …

Improving the efficacy of chemoradiation with targeted agents

MA Morgan, LA Parsels, J Maybaum, TS Lawrence - Cancer discovery, 2014 - AACR
… Thorough preclinical studies to evaluate key issues such as mechanisms of interaction, …
and whether a patient will benefit from the radiosensitizing or chemosensitizing properties of a …

Chemotherapy and chemosensitization of non–small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9

H Wang, ER Rayburn, W Wang, ER Kandimalla… - Molecular cancer …, 2006 - AACR
… in clinical or preclinical development and antisense … oligonucleotides have been evaluated
in models of human … in phase II clinical trials in cancer patients. This present study was …

Preclinical evaluations of therapies combining the vascular targeting agent combretastatin A-4 disodium phosphate and conventional anticancer therapies in the …

L Li, AM Rojiani, DW Siemann - Acta Oncologica, 2002 - Taylor & Francis
… ought to be considered as a candidate agent for therapeutic evaluation in AIDS-KS patients.
Chemosensitization of CCNU in KHT murine tumor cells in vivo and in vitro by the agent RB …

[HTML][HTML] A pilot trial of G3139, a bcl-2 antisense oligonucleotide, and paclitaxel in patients with chemorefractory small-cell lung cancer

CM Rudin, GA Otterson, AM Mauer… - Annals of oncology, 2002 - Elsevier
Preclinical studies have demonstrated synergy … this patient was similar to the intermediate
levels of suppression (60% of baseline) associated with evident chemosensitization in patients

Multi-institutional phase I study of low-dose ultra-fractionated radiotherapy as a chemosensitizer for gemcitabine and erlotinib in patients with locally advanced or …

A Konski, JE Meyer, M Joiner, MJ Hall, P Philip… - Radiotherapy and …, 2014 - Elsevier
… Whether this can be utilized to significant advantage in external-beam radiotherapy has
been difficult to definitively demonstrate, with extensive preclinical studies on human tumor …

Chemoprotective and chemosensitizing effects of apigenin on cancer therapy

Z Nozhat, S Heydarzadeh, Z Memariani… - Cancer Cell …, 2021 - Springer
… xenograft models, or clinical trials in cancer patients. In Biosystems, the combination of two
… effects, and other side effects leading to patient’s death. However, radiosensitizing agents …

Phytochemicals in cancer treatment: From preclinical studies to clinical practice

AS Choudhari, PC Mandave, M Deshpande… - Frontiers in …, 2020 - frontiersin.org
… use of anticancer drugs and thus impair patient’s quality of life. … treatment efficiency in cancer
patients and decrease adverse … In the present review, an attempt has been made to gather …

Nutrition modulation of gastrointestinal toxicity related to cancer chemotherapy: from preclinical findings to clinical strategy

H Xue, MB Sawyer, PE Wischmeyer… - Journal of Parenteral …, 2011 - Wiley Online Library
… function in cancer chemotherapy patients. Available evidence … 3 PUFAs is that its
chemosensitizing effect must be substantially … Many preclinical studies used healthy animals to …

Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer

MG Espey, P Chen, B Chalmers, J Drisko… - Free Radical Biology …, 2011 - Elsevier
… Standard therapy for patients with metastatic pancreatic … Gemcitabine offers clinical benefit
in an adjuvant setting for patientsEvaluation of the chemosensitizing effects of ascorbate and …