… in the mouse that … exertional heat stroke (EHS) and related exertional heat injuries can
occur when there is an inability to adequately dissipate the heat load induced by physical exertion…

… models of CHS have been well established. This protocol aims to provide guidelines for a
refined preclinical mouse model of … , rectal probes, or electric shock. Male and female C57Bl/6 …

… Relatively little information is available about the effect of an acute exertional heat stroke (EHS)
on myocardium structure and function. Herein, we used a survival male rat model of EHS …

… Heatstroke is a heat illness characterized by the rapid rise of core body temperature above …
heat and as exertional when it develops during strenuous exercise. Classic heatstroke occurs …

… Preclinical models of classic heat stroke and EHS show a robust inflammatory response
that ensues after collapse, which mimics mechanisms observed in patients. In both male and …

… Exertional heat stroke (EHS) is a potentially lethal condition resulting from high core body …
We established a mouse model of severe EHS to identify mechanisms of hyperthermia/…

… Studies in cell lines and large animal models have demonstrated that extreme heat directly
… Risk factors additionally unique to exertional heat illness include over- motivation of the …

… utilizes a translational model between animal and human research to explore possible
physical and physiological differences with respect to risk and treatment of exertional heat stroke. …

… Exertional heat stroke (EHS) and related exertional heat injuries can occur when there is
an 50 inability to adequately dissipate the heat load induced by physical exertion, resulting in …

… Exertional heat stroke transiently increased expression of acute phase proteins in mouse …
The APR to heat stroke in either humans or animal models has received little attention in the …