Animal models of traumatic brain injury
Y Xiong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
… 24,25 , weight-drop impact acceleration injury 26 and blast injury 27,28 (Fig. 1; Tables 1,2). …
animal models of TBI. We do not discuss cerebellar injury models, as direct cerebellar injury …
animal models of TBI. We do not discuss cerebellar injury models, as direct cerebellar injury …
An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms
A Fesharaki-Zadeh, D Datta - Frontiers in cellular neuroscience, 2024 - frontiersin.org
… preclinical models, including classic preclinical models including … animal models included
in this study are the fluid percussion injury (FPI) model (Xiong et al., 2013), weight drop injury …
in this study are the fluid percussion injury (FPI) model (Xiong et al., 2013), weight drop injury …
Animal models of traumatic brain injury: a critical evaluation
… in brain injured patients (against all classes of symptoms) can be predicted. In this review,
six established animal models of head trauma, … While no single animal model is entirely …
six established animal models of head trauma, … While no single animal model is entirely …
Roadmap for advancing pre-clinical science in traumatic brain injury
… Pre-clinical models of disease have long played important roles in the advancement of new
treatments. However, in traumatic brain injury … and pitfalls of pre-clinical models with the goal …
treatments. However, in traumatic brain injury … and pitfalls of pre-clinical models with the goal …
Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?
N Marklund, L Hillered - British journal of pharmacology, 2011 - Wiley Online Library
… Traumatic brain injury (TBI) is the leading cause of death and disability in young … animal
models of TBI for preclinical evaluation of pharmacological compounds. No single animal model …
models of TBI for preclinical evaluation of pharmacological compounds. No single animal model …
Animal models of traumatic brain injury
… Representative sections of a mouse brain showing IgG extravasation 48 … model of traumatic
brain injury. This demonstrates marked blood–brain barrier disruption caused by this model. …
brain injury. This demonstrates marked blood–brain barrier disruption caused by this model. …
Animal models of traumatic brain injury: is there an optimal model to reproduce human brain injury in the laboratory?
MC Morganti-Kossmann, E Yan, N Bye - Injury, 2010 - Elsevier
… some characteristics of models of TBI in relation to focal and diffuse brain injury. A particular
emphasis was given only to the most widely applied or pioneering animal models to give the …
emphasis was given only to the most widely applied or pioneering animal models to give the …
Animal models of traumatic brain injury and assessment of injury severity
… special focus on mixed injury that represents a translational concussive head injury. We will
classify animal models of TBI broadly into focal injury, diffuse injury, and mixed injury. Focal …
classify animal models of TBI broadly into focal injury, diffuse injury, and mixed injury. Focal …
Workshop on animal models of traumatic brain injury
JT POVLISHOCK, RL Hayes, ME MICHEL… - Journal of …, 1994 - liebertpub.com
… Consistent with the issues identified in the preceding passage, the workshop was organized
around a general framework as follows: Section I), consideration of human traumatic brain …
around a general framework as follows: Section I), consideration of human traumatic brain …
Large animal models of traumatic brain injury
R Vink - Journal of neuroscience research, 2018 - Wiley Online Library
… Animal models are essential to gain a deeper understanding of the pathophysiology associated
with traumatic brain injury (TBI). Rodent models of TBI have proven highly valuable with …
with traumatic brain injury (TBI). Rodent models of TBI have proven highly valuable with …
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