The current state of preclinical prostate cancer animal models

KJ Pienta, C Abate‐Shen, DB Agus, RM Attar… - … Prostate, 2008 - Wiley Online Library
Prostate Cancer Foundation held a Prostate Cancer Models … the state of prostate cancer
preclinical models and identified … genetically engineered mouse models that have hampered …

[HTML][HTML] Cellular and molecular progression of prostate cancer: models for basic and preclinical research

S Saranyutanon, SK Deshmukh, S Dasgupta, S Pai… - Cancers, 2020 - mdpi.com
… cellular and molecular progression of prostate cancer. We also discuss available model
systems and their tested and potential utility in basic and preclinical prostate cancer research. …

[HTML][HTML] Preclinical models in prostate cancer: Resistance to AR targeting therapies in prostate cancer

W Devlies, F Handle, G Devos, S Joniau, F Claessens - Cancers, 2021 - mdpi.com
… androgen receptor targeted therapies in prostate cancer. This will encompass both the
different existing preclinical models as well as the role specific models have played in the current …

Preclinical mouse models of human prostate cancer and their utility in drug discovery

SI Park, SJ Kim, LK McCauley… - Current protocols in …, 2010 - Wiley Online Library
… Numerous preclinical animal models of prostate cancer are available, including … models
and human prostate cancer xenograft mouse models. In contrast to transgenic mouse models

Preclinical models of prostate cancer

K Fizazi, NM Navone - Bulletin du Cancer, 2005 - jle.com
… Clinical and experimental progression of a new model of human prostate cancer and therapeutic
… A metastatic and androgen-sensitive human prostate cancer model using intraprostatic …

A preclinical xenograft model of prostate cancer using human tumors

…, Australian Prostate Cancer BioResource… - Nature protocols, 2013 - nature.com
… with diagnosis and prognosis of prostate cancer 17,18 . Although many models of prostate
cancer only focus on the epithelial … Cancer-associated fibroblasts (CAFs) isolated from human …

[HTML][HTML] Application of prostate cancer models for preclinical study: advantages and limitations of cell lines, patient-derived xenografts, and three-dimensional culture …

T Namekawa, K Ikeda, K Horie-Inoue, S Inoue - Cells, 2019 - mdpi.com
preclinical model cell lines and their sublines, PDXs, and patient-derived organoid and spheroid
models… Patient-derived xenografts (PDXs) are an important preclinical cancer model for …

Model systems of prostate cancer: uses and limitations

NM Navone, CJ Logothetis… - Cancer and metastasis …, 1998 - Springer
… of prostate cancer progression. In this review we summarize the properties of the prostate
cancer model … This review will guide the investigator seeking models with which to test specific …

[HTML][HTML] From genomics to functions: preclinical mouse models for understanding oncogenic pathways in prostate cancer

C Yu, K Hu, D Nguyen, ZA Wang - American Journal of Cancer …, 2019 - ncbi.nlm.nih.gov
… experimental models, such as cancer cell lines, animal models… Here, we review the current
preclinical mouse models for … the power of genetically engineered mouse models (GEMMs) in …

[HTML][HTML] Canine prostate models in preclinical studies of minimally invasive interventions: Part I, canine prostate anatomy and prostate cancer models

F Sun, C Báez-Díaz… - … andrology and urology, 2017 - ncbi.nlm.nih.gov
preclinical investigation, the low incidence and pathological features limit its utility. Alternatively,
canine orthotopic PCa models have a great potential in preclinical … the canine prostate, …