… castration-resistant prostate cancer following disease … evaluated in preclinical prostate cancer
models of enzalutamide … subcutaneous VCaP xenograft models. Correlative assessments …

… a preclinical model to be transferred to patients as well as transferring clinical evidence to
preclinical models … The tight connection between preclinical and clinical PET molecular studies …

… We first established a mouse model of prostate cancer by deleting the tumor suppressor
Pten in prostatic epithelial cells using the Probasin (PBi)-Cre promoter (Pten fl/fl .PB-Cre) (30). …

… experimental models, such as cancer cell lines, animal models… Here, we review the current
preclinical mouse models for … the power of genetically engineered mouse models (GEMMs) in …

… model for cancer research. This review focuses on current prostate cancer preclinical models
… (iPSCs) could hold promise for prostate disease modelling and personalised medicine. …

… Given the conservation in the molecular programs affected by drug treatment in the GEM
models and human prostate cancer, we next asked whether we could use the mouse treatment …

… and patient-derived xenograft (PDX) models, representing the androgen-responsive PCa …
preclinical models in combination with androgen deprivation. In a PTEN-negative PDX model, …

… We have developed several prostate cancer mouse models that have specific benefits and
… We developed several prostate cancer orthotopic models in which different prostate cancer …

… a comprehensive view of the available models for NEPC detailing their … of preclinical
models to better study, prevent, or reverse NEPC. The integration of multiple preclinical models …

… Using an orthotopic preclinical model of prostate cancer, we tested the hypotheses that, after
exercise training, in the tumor, there would be an enhanced microvascular Po 2 , increased …