[HTML][HTML] Canine prostate models in preclinical studies of minimally invasive interventions: part II, benign prostatic hyperplasia models

F Sun, C Báez-Díaz… - … andrology and urology, 2017 - ncbi.nlm.nih.gov
… Canine prostate is widely used as animal model in the preclinical evaluation of emerging
therapeutic interventions. Spontaneous benign prostatic hyperplasia (BPH) is common in adult …

Preclinical antitumor activity of the diindolylmethane formulation in xenograft mouse model of prostate cancer

VI Kiselev, VM Drukh, EL Muyzhnek… - Experimental …, 2014 - irbis-nbuv.gov.ua
… We decided to carry out preclinical in vivo study of … Prostate cancer (PC) is one of the most
common cancers in the world affecting men. PC in Europe is 2""/3“’ cause of cancer deaths, in …

… prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer …

KM Haram, HJ Peltier, B Lu, M Bhasin, HH Otu… - … Prostate, 2008 - Wiley Online Library
model array data with two recent human prostate cancer studies [14,15], we found that Sox4
and Tubb2a are especially relevant targets in human prostate cancer therapeutic studies. …

The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer

K Dredge, JA Kink, RM Johnson, I Bytheway… - Cancer chemotherapy …, 2009 - Springer
… The aim of the present study was to determine the effect of PG11047 in a non-small cell
lung cancer model alone and in combination with cisplatin, and in a prostate cancer model, …

Genetically defined mouse models that mimic natural aspects of human prostate cancer development.

P Roy-Burman, H Wu, WC Powell… - … -related cancer, 2004 - erc.bioscientifica.com
… for initiating the essential preclinical tests of potential … models of prostate cancer to recapture
eventually all of the pathophysiological characteristics of the human disease. The models

Synthesis and Preclinical Evaluation of [18F]SiFA-PSMA Inhibitors in a Prostate Cancer Model

JJ Bailey, M Wuest, M Wagner… - Journal of Medicinal …, 2021 - ACS Publications
Prostate cancer represents a histologically and clinically very heterogeneous disease. It can
… (1) Many identified prostate cancers are not life-threatening as they typically progress slowly…

Alpha-PET for Prostate Cancer: Preclinical investigation using 149Tb-PSMA-617

CA Umbricht, U Köster, P Bernhardt, N Gracheva… - Scientific reports, 2019 - nature.com
… In this study, it was aimed to investigate 149 Tb-PSMA-617 for targeted α-therapy (TAT) using
a mouse model of prostate-specific membrane antigen (PSMA)-expressing prostate cancer

Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate …

SM Hillier, KP Maresca, FJ Femia, JC Marquis… - Cancer research, 2009 - AACR
Prostate-specific membrane antigen (PSMA) is expressed in normal human prostate epithelium
and is highly up-regulated in prostate cancer. We previously reported a series of novel …

green tea polyphenols in chemoprevention of prostate cancer: preclinical and clinical studies

N Khan, VM Adhami, H Mukhtar - Nutrition and cancer, 2009 - Taylor & Francis
Prostate cancer (PCa) is one of the most common cancers in men in the United States and is
the second leading cause of male cancer death worldwide after lung cancer… animal models, …

Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models

X Li, Y Chen, L Bai, R Zhao, Y Wu, ZR Xie… - … Journal of Cancer, 2023 - nature.com
… Our findings provided the first preclinical evidence supporting nicardipine as a novel
EED inhibitor that has the potential to be promptly tested in PCa patients to overcome …