… is sufficient to predict novel therapeutic targets effectively and confirms that this type of
evidence is essential for formulating or strengthening hypotheses in the target discovery process. …

… prediction of novel therapeutic targets for anti-cancer therapy. We … model interpretation, and
make predictions for more than 15,000 … ranked lists of putative novel targets per cancer type, …

… prediction, diagnostic, and treatment efforts. Reliable biomarkers that can differentiate between
… subgroups, predict worsening symptoms, or suggest novel therapeutic targets would be …

… Here we introduce a novel computational method based on the coupling between fuzzy
logic modeling and a global optimization algorithm, whose aims are to (1) predict the emergent …

… colon cancer also suggests that it is a potential therapeutic target. … Msi-1 is a novel prognostic
marker to predict the outcome of colon … Msi-1 as a new therapeutic target for colon cancer. …

… , inhibition of Nrf2 would represent a novel therapeutic method that could improve survival of
… The prediction implies that Polythiazide may be an Nrf2 modulator with therapeutic potential …

… was predicted using the 144 core genes in the colon cancer ceRNA network for the first time,
to the best of the authors' knowledge, which may represent a novel therapeutic target for the …

… therapeutic target. Here we report Cdc7 as an independent prognostic biomarker and novel
therapeutic target in … , and was found to be an independent predictor of disease-free survival. …

… analysis on drug targets. All these findings suggest that our approach is effective for accurate
predicting novel therapeutic options for HCC and easily to be extended to other tumors. …

… In this study, we attempted to explore the potential molecular mechanisms of DN based
on the bioinformatics methods and to provide a prospective novel therapeutic target. In the …