Review: Predictive and prognostic markers for epidermal growth factor receptor inhibitor
therapy in non-small cell lung cancer Page 1 Predictive and prognostic markers for epidermal …

… , each EGFR TKI inhibitor may have a unique set of predictive markers. The challenge is …
predictive markers for each EGFR inhibitor. Recent studies also suggest that a predictive marker …

… emerged as an important predictive marker of resistance to … The epidermal growth factor
receptor (EGFR), a member of … is not predictive of response to EGFR inhibitors. It is now clear …

… This review will discuss potential predictive molecular markers of response and resistance
to EGFRtargeted therapies in mCRC, NSCLC and breast cancer. We will focus on the …

… Epidermal growth factor receptor inhibitors in colorectal cancer: It’s time to get back on target…
Analysis of epidermal growth factor receptor expression as a predictive factor for response …

… growth factor (VEGF) levels from three randomized, phase II clinical studies of vandetanib
(oral VEGF/epidermal growth factor receptor inhibitor… epidermal growth factor receptor inhibitor …

The human epidermal growth factor receptor (HER1/EGFR/ErbB1) signaling is aberrant and
overexpressed in many solid malignancies making it an appealing target for biologic agents…

… 121 Hegazy R, Hegazy A, Kamel M, El-Farargy O, Nawar N, El-Atar A: Role of human epidermal
growth factor receptor 2 antagonist (Trastuzumab) in the management of nonmuscle-…

… In investigations to identify predictive markers of response to … patients after treatment with
EGFR inhibitors,17 and reduced … attempt to identify predictive markers of response to gefitinib. …

… trial design, they have not resulted in the identification of a validated, predictive marker for
antitumour efficacy. Molecular imaging of pharmacodynamic effects and visualisation of target …