Risk of bleeding with oral anticoagulants: an updated systematic review and performance analysis of clinical prediction rules

P Loewen, K Dahri - Annals of hematology, 2011 - Springer
… risk estimation tools for patients on oral anticoagulant therapy has been made since 2006 …
prediction rules (CPRs) available for estimating bleeding risk in patients on oral anticoagulant

The role of adherence thresholds for development and performance aspects of a prediction model for direct oral anticoagulation adherence

C Ruff, L Koukalova, WE Haefeli… - Frontiers in Pharmacology, 2019 - frontiersin.org
… For example, if direct oral anticoagulants (DOAC) are not taken continuously, an … for
predictive classification. Thus, the threshold can determine the prediction model’s performance to …

Evaluation of the predictive performance of bleeding risk scores in patients with non‐valvular atrial fibrillation on oral anticoagulants

SA Beshir, Z Aziz, LB Yap, KH Chee… - Journal of Clinical …, 2018 - Wiley Online Library
… To the best of our knowledge, this is the first evaluation study of the predictive performance
… novel oral anticoagulant users. These BRSs show poor to acceptable predictive performance

Novel bleeding prediction model in atrial fibrillation patients on new oral anticoagulants

O Barnett-Griness, N Stein, A Kotler, W Saliba… - Heart, 2022 - heart.bmj.com
… Existing clinical models had been generated for the prediction of bleeding risk associated
with the older vitamin K antagonists or antiplatelet therapy.7–9 Predictive performance of the …

Development and validation of the DOAC score: a novel bleeding risk prediction tool for patients with atrial fibrillation on direct-acting oral anticoagulants

R Aggarwal, CT Ruff, S Virdone, S Perreault… - Circulation, 2023 - Am Heart Assoc
… The DOAC Score had stronger predictive performance than the HAS-BLED score in both
validation cohorts, including 25 586 individuals in COMBINE-AF (C statistic, 0.67 versus 0.63; P …

Predictors of pre-procedural concentrations of direct oral anticoagulants: a prospective multicentre study

A Godier, AS Dincq, AC Martin, A Radu… - European heart …, 2017 - academic.oup.com
… the hypothesis that creatinine clearance would be a predictive factor of pre-procedural DOAC
… The performance of the predictive model was assessed by both the concordance statistic (…

Scores to predict major bleeding risk during oral anticoagulation therapy: a prospective validation study

J Donzé, N Rodondi, G Waeber, P Monney… - The American journal of …, 2012 - Elsevier
… /benefit of oral anticoagulant therapy. We aimed to externally validate and compare the …
performance of 7 clinical prediction scores for major bleeding events during oral anticoagulation

A new model to predict major bleeding in patients with atrial fibrillation using warfarin or direct oral anticoagulants

JNS Claxton, RF MacLehose, PL Lutsey, FL Norby… - PloS one, 2018 - journals.plos.org
… Patients with non-valvular AF initiating oral anticoagulation were identified in the … that
selected variables predicting major bleeding in the first year after anticoagulant initiation. The final …

Can machine learning from real-world data support drug treatment decisions? A prediction modeling case for direct oral anticoagulants

AD Meid, L Wirbka, ARMIN Study Group… - Medical Decision …, 2022 - journals.sagepub.com
… This study was a predictive modeling study in a previously defined cohort of DOAC patients
(… for “Transparent reporting of a multivariable prediction model for individual prognosis or …

Validation of bleeding risk prediction scores for patients with major bleeding on direct oral anticoagulants

S Tchen, N Ryba, V Patel… - Annals of …, 2020 - journals.sagepub.com
Oral anticoagulant–associated harm has been recognized … and Prevention have implicated
oral anticoagulants as the … of bleeding associated with oral anticoagulant use. The most …