… , the predictive performance of our model was not better than that of other models based on
… infusion had no apparent impact on the predictive performance of published PopPK models. …

This study aimed to determine the stability (in terms of covariate selection) of a population
pharmacokinetic model and evaluate its performance in the absence of a test data set. Data …

… Recently a pediatric pharmacokinetic (PK) model was developed for busulfan to explain the
… This study assesses the predictive performance of this busulfan PK model in a new, more …

… pharmacokinetic models … pharmacokinetic model was recently published. The current study
sought to externally evaluate the predictive performance and generalizability of this model. …

… adjustment, their predictive performance should be externally evaluated. This study tested
the predictive performance of all published population pharmacokinetic models of tobramycin …

… attention to its pharmacokinetic and pharmacodynamic … physiologically based pharmacokinetic
(PBPK) model, predicting ADME … A PBPK model for adults was developed using PK-Sim® …

… In a real-data example, predictive performance of the model is … , predictive performance is
presented wrt the covariate model (… mate) and also put in relation to having no covariate model. …

… This review defines the common aspects of population pharmacokinetic modelling through
a … be on model-predictive performance and not all population pharmacokinetic models need …

… the predictive performance of a pharmacokinetic model for extrapolation purposes, here
we also evaluate whether the covariate point estimate should be retained in the model when …

… Model validation procedures are crucial when models are to be used to develop new … the
predictive performance of a previously published paediatric population pharmacokinetic model …