Antiviral drugs for cytomegalovirus in transplant recipients: advantages of preemptive therapy

N Singh - Reviews in medical virology, 2006 - Wiley Online Library
transplant recipients who received valganciclovir prophylaxis for 100 days [11]. In stem
cell transplant recipients, preemptive therapy … for solid organ transplant recipients. Meta-analyses …

Preemptive therapy versus universal prophylaxis with ganciclovir for cytomegalovirus in solid organ transplant recipients

N Singh - Clinical infectious diseases, 2001 - academic.oup.com
… At present, preemptive therapy for transplant recipients may be based on results of the
antigenemia test or quantitative PCR, depending on access to the tests. The novel application of …

Cytomegalovirus replication kinetics in solid organ transplant recipients managed by preemptive therapy

SF Atabani, C Smith, C Atkinson… - … of Transplantation, 2012 - Wiley Online Library
recipient. In this study, serial blood samples from 689 kidney or liver transplant recipients
were … CMV was managed using preemptive antiviral therapy and no patient received antiviral …

Pre-emptive treatment for cytomegalovirus viremia to prevent cytomegalovirus disease in solid organ transplant recipients

GFM Strippoli, EM Hodson, C Jones, JC Craig - Transplantation, 2006 - journals.lww.com
Preemptive therapy is effective compared with placebo or standard care, but additional …
preemptive therapy and prophylaxis to prevent CMV disease in solid organ transplant recipients. …

High incidence of ganciclovir-resistant cytomegalovirus infection among lung transplant recipients receiving preemptive therapy

AP Limaye, G Raghu, DM Koelle… - The Journal of …, 2002 - academic.oup.com
… In conclusion, ganciclovir resistance is common in lung transplant recipients, especially D +
/R − patients. The preemptive therapy directed at pp65 antigenemia used in this study was of …

Effect of preemptive therapy vs antiviral prophylaxis on cytomegalovirus disease in seronegative liver transplant recipients with seropositive donors: a randomized …

N Singh, DJ Winston, RR Razonable, GM Lyon… - Jama, 2020 - jamanetwork.com
transplant recipients with seropositive donors, high rates of delayed-onset postprophylaxis
CMV disease occur. An alternate approach, preemptive therapy (initiation of antiviral therapy

[HTML][HTML] High incidence of anticytomegalovirus drug resistance among D+ R− kidney transplant recipients receiving preemptive therapy

L Couzi, S Helou, T Bachelet, K Moreau… - … of Transplantation, 2012 - Elsevier
… mutations) was also more frequent in the preemptive group (16% vs. 3… In summary, preemptive
therapy in D+R− KTR with high … In conclusion, preemptive therapy is associated with high …

[PDF][PDF] Prophylaxis versus preemptive therapy for cytomegalovirus disease in high‐risk liver transplant recipients

M Bodro, N Sabé, L Lladó, C Baliellas… - … Transplantation, 2012 - Wiley Online Library
… In this study, we compared prophylaxis and preemptive therapy for the … /recipient-seronegative
(Dþ/RÀ) liver recipients. To this end, we selected a retrospective cohort of liver recipients (…

Preemptive therapy for the prevention of cytomegalovirus disease in renal transplant recipients: our preliminary experience

N Paudice, A Mehmetaj, M Zanazzi, L Moscarelli… - Transplantation …, 2009 - Elsevier
… of morbidity in renal transplant recipients. We report our preliminary evaluation of the efficacy
and security of preemptive therapy to manage renal transplant recipients with evidence of …

Clinical impact of neutropenia related with the preemptive therapy of CMV infection in solid organ transplant recipients

C Martín-Gandul, P Pérez-Romero… - Journal of Infection, 2014 - Elsevier
… In the present study, SOT recipients receiving valganciclovir preemptive therapy for CMV
infection frequently developed hematological toxicity, especially neutropenia. However, and …