Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro

GA Thouas, AO Trounson, EJ Wolvetang… - Biology of …, 2004 - academic.oup.com
mitochondrial dysfunction has been proposed as a cause of high levels of developmental
retardation and arrest that occur in human preimplantation embryosmitochondrial dysfunction

Mitochondrial dysfunction of in vitro grown rabbit oocytes results in preimplantation embryo arrest after activation

H Kanaya, S Hashimoto, T Teramura… - … of Reproduction and …, 2007 - jstage.jst.go.jp
… of cells with mitochondria damage [31]. In this study, developmental arrest was reversed
once the nucleus of an IVG oocyte was transplanted into ovulated ooplasm. Thus, mitochondria

Mitochondrial dysfunction in reproduction

RPS Jansen, GJ Burton - Mitochondrion, 2004 - Elsevier
… Even without exogenous purines the embryos of many species tend to arrest at this stage
during … Protection is also offered to the preimplantation embryo in vivo by the presence of non-…

Molecular drivers of developmental arrest in the human preimplantation embryo: a systematic review and critical analysis leading to mapping future research

K Sfakianoudis, E Maziotis, E Karantzali… - International journal of …, 2021 - mdpi.com
embryos, unveiling the importance of proper mitochondrial function at the earliest stages of
development [33]. A mitochondrial dysfunction … -1) gene in arrested embryos as an extensive …

The role of mitochondrial dynamics in oocyte and early embryo development

RM Yildirim, E Seli - Seminars in Cell & Developmental Biology, 2024 - Elsevier
… during gamete and pre-implantation embryo development. … of the profound impact
mitochondrial dysfunction may have on … and cell cycle arrest specifically at the 2-cell embryo

Mfn2 affects embryo development via mitochondrial dysfunction and apoptosis

N Zhao, Y Zhang, Q Liu, W Xiang - PloS one, 2015 - journals.plos.org
… ATP and mtDNA levels and mitochondrial membrane potential… preimplantation embryo
development through mitochondrial … mouse preimplantation embryos by obstructing mitochondrial

[HTML][HTML] The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos: a mechanistic study

MH Kang, J Das, S Gurunathan, HW Park, H Song… - Theranostics, 2017 - ncbi.nlm.nih.gov
… and mitochondrial dysfunction in morula stage embryosarrested morula stage embryos To
examine whether DMSO induced mitophagy and autophagy in arrested morula stage embryos

Permanent embryo arrest: molecular and cellular concepts

DH Betts, P Madan - MHR: Basic science of reproductive …, 2008 - academic.oup.com
mitochondrial dysfunction, … preimplantation development and on the amount of ROS
generated, the oxidative stress-induced telomere uncapping may lead to permanent embryo arrest

[PDF][PDF] Mitochondrial membrane potential in 2-cell stage embryos correlates with the success of preimplantation development

K Komatsu, A Iwase, M Mawatari, J Wang… - Reproduction, 2014 - Citeseer
… that the development of embryos with low DJm tended to be arrested between the 2- and 4-…
2004 Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in …

Sirt3 protects in vitro–fertilized mouse preimplantation embryos against oxidative stress–induced p53-mediated developmental arrest

Y Kawamura, Y Uchijima, N Horike… - The Journal of …, 2010 - Am Soc Clin Investig
… Involvement of mitochondrial dysfunction in this process has … Sirt3 has been described as
a mitochondrial sirtuin, but … Sirt3 localizes to mitochondria in preimplantation embryos, we …