Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxin
M Muller - Free Radical Biology and Medicine, 2006 - Elsevier
… in cell death due to apoptosis. A549 cells exposed to pyocyanin generated hydrogen peroxide
in a dose-dependent manner and the senescence-… of premature cellular senescence by …
in a dose-dependent manner and the senescence-… of premature cellular senescence by …
Obesity and type-2 diabetes as inducers of premature cellular senescence and ageing
DGA Burton, RGA Faragher - Biogerontology, 2018 - Springer
… Cellular senescence may be one … of premature cell senescence in other tissues. As such,
the mechanisms and processes by which obesity and diabetes promote premature senescence …
the mechanisms and processes by which obesity and diabetes promote premature senescence …
Radiation-induced premature cellular senescence involved in glomerular diseases in rats
S Aratani, M Tagawa, S Nagasaka, Y Sakai… - Scientific Reports, 2018 - nature.com
… Currently, cellular senescence has emerged as a … cellular senescence. Although the kidney
is known as a radiosensitive organ, whether and how radiation-induced cellular senescence …
is known as a radiosensitive organ, whether and how radiation-induced cellular senescence …
… in A-type lamins and to HIV protease inhibitor therapy are both associated with prelamin A accumulation, oxidative stress and premature cellular senescence
M Caron, M Auclair, B Donadille, V Bereziat… - Cell Death & …, 2007 - nature.com
… of mitochondrial respiratory chain proteins and premature cellular senescence. Inhibition of
prelamin A farnesylation prevented cellular senescence and oxidative stress. Adipose tissue …
prelamin A farnesylation prevented cellular senescence and oxidative stress. Adipose tissue …
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Premature cell senescence in human skin: Dual face in chronic acquired pigmentary disorders
B Bellei, M Picardo - Ageing Research Reviews, 2020 - Elsevier
… characteristic, it was recently recognized that senescence is physiologically and … of cellular
senescence has expanded to include the growth arrest caused by various cellular stresses, …
senescence has expanded to include the growth arrest caused by various cellular stresses, …
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
M Serrano, AW Lin, ME McCurrach, D Beach, SW Lowe - Cell, 1997 - cell.com
… of oncogenic ras induces a cell-cycle arrest involving p53 and p16 that is indistinguishable
from cellular senescence. We suggest that premature senescence is a mechanism of tumor …
from cellular senescence. We suggest that premature senescence is a mechanism of tumor …
Cellular senescence and cancer treatment
CA Schmitt - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2007 - Elsevier
… premature senescence as a tumor suppressor mechanism, a growing line of evidence identifies
cellular senescence … review will mostly focus on cellular senescence that occurs in late …
cellular senescence … review will mostly focus on cellular senescence that occurs in late …
Ionizing irradiation inhibits keloid fibroblast cell proliferation and induces premature cellular senescence
J Ji, Y Tian, Y Zhu, L Zhang, S Ji, J Huan… - The Journal of …, 2015 - Wiley Online Library
… , our data indicate that X-ray radiation may prevent the recurrence of keloids by controlling
fibroblast proliferation, arresting the cell cycle and inducing premature cellular senescence. …
fibroblast proliferation, arresting the cell cycle and inducing premature cellular senescence. …
Lycorine hydrochloride suppresses stress‐induced premature cellular senescence by stabilizing the genome of human cells
… However, whether lycorine is involved in delaying the onset of cellular senescence and its
… -induced premature cellular senescence (SIPS) by ~2-fold, as determined by senescence-…
… -induced premature cellular senescence (SIPS) by ~2-fold, as determined by senescence-…
Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence
EK Benson, SW Lee, SA Aaronson - Journal of cell science, 2010 - journals.biologists.com
… To directly investigate the involvement of p53 and Rb pathways in the premature cellular
senescence exhibited by HGPS fibroblasts, we infected HGPS fibroblasts that were near the …
senescence exhibited by HGPS fibroblasts, we infected HGPS fibroblasts that were near the …