Dementia risk and prevention by targeting modifiable vascular risk factors

S Tariq, PA Barber - Journal of neurochemistry, 2018 - Wiley Online Library
… Reitz et al. 2007), and dementia (Launer et al. 2000; Yamada … risk factors on the risk of
late-life dementia. We discuss the use of biological markers of preclinical disease to identify at risk-…

Association between midlife dementia risk factors and longitudinal brain atrophy: the PREVENT-Dementia study

JT O'Brien, MJ Firbank, K Ritchie, K Wells… - Journal of Neurology …, 2020 - jnnp.bmj.com
… are associated with future risk of dementia in asymptomatic … Risk Factors, Aging, and Dementia
(CAIDE) risk score and … ) from the PREVENT-Dementia programme underwent MRI scans …

Prevention of dementia by targeting risk factors

M Kivimäki, A Singh-Manoux - The Lancet, 2018 - thelancet.com
… of dementia prevention, although the estimate based on the proposed risk factors is likely to
… PAF is an integrate measure, which reflects the prevalence of the risk factor in the population …

Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors

K Ritchie, I Carrière, CW Ritchie, C Berr, S Artero… - Bmj, 2010 - bmj.com
… ogy, and targeting risk factors likely to decrease … risk factors for dementia that have already
been identified by population studies using internationally recognised algorithms for dementia

Does treating vascular risk factors prevent dementia and Alzheimer's disease? A systematic review and meta-analysis

SC Larsson, HS Markus - Journal of Alzheimer's disease, 2018 - content.iospress.com
… significant reduced risk of dementia in RCTs (n= 5; relative risk [… –1.01) and with reduced
AD risk in prospective studies (n= 5; … of antidiabetic drugs or insulin therapy on dementia risk. …

One third of dementia cases can be prevented within the next 25 years by tackling risk factors. The case “for” and “against”

M Montero-Odasso, Z Ismail, G Livingston - Alzheimer's Research & …, 2020 - Springer
… or prevent dementia. It concluded that up to 35% of dementia could be prevented by modifying
nine risk factors: … of risk factors can be done by lifestyle interventions, which can influence …

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

M Kivipelto, F Mangialasche, T Ngandu - Nature Reviews Neurology, 2018 - nature.com
risk factors and results from novel trials aiming to prevent … studies on risk factors and protective
factors for dementia and AD… prevention on the basis of the management of lifestyle-related …

Preventing dementia

N Purandare, C Ballard, A Burns - Advances in psychiatric treatment, 2005 - cambridge.org
… focus on one or two risk factors and include cognition or dementia only as a secondary …
multiple risk factors in atrisk people with mild cognitive impairment, with incident dementia

Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies

K Deckers, MPJ van Boxtel… - … journal of geriatric …, 2015 - Wiley Online Library
Dementia has a multifactorial etiology, but the importance of individual health and lifestyle
related risk factors … is to identify the major modifiable risk factors for dementia as a first step in …

The PREVENT Dementia programme: Baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia

CW Ritchie, K Bridgeman, S Gregory… - Brain …, 2024 - academic.oup.com
… Materials and methods: the PREVENT dementia protocol In this paper, the PREVENT dementia
baseline data are described and distributions of key risk and outcome variables relevant …