From the Editor: The future of managing lipoprotein disorders

WV Brown - Journal of Clinical Lipidology, 2013 - lipidjournal.com
… Both NHLBAC working groups facilitated our evaluation of the existing landscape and … , to
assume the governance and management of these prevention guidelines and to ensure their …

New insights in the control of low-density lipoprotein cholesterol to prevent cardiovascular disease

JL Katzmann, U Laufs - Current Cardiology Reports, 2019 - Springer
prevention by mechanisms that increase the hepatic clearance of apolipoprotein B-containing
lipoproteins … Bempedoic acid is currently evaluated in the CLEAR Outcomes trial of statin-…

High density lipoprotein cholesterol: an evolving target of therapy in the management of cardiovascular disease

NK Kapur, D Ashen, RS Blumenthal - … health and risk management, 2008 - Taylor & Francis
… This study was the first primary prevention study to show that individuals with HDL-C <40
mg/dL … This study evaluated the effect of exogenous administration of ETC-216 on coronary …

Targeting cholesteryl ester transfer protein for the prevention and management of cardiovascular disease

PJ Barter, JJP Kastelein - Journal of the American College of Cardiology, 2006 - jacc.org
… Very low-density lipoproteins are subsequently converted into … the lipoprotein profile and
may potentially be a new strategy for reducing CVD. Large-scale, randomized trials evaluating

Lipoprotein (a) for risk assessment in patients with established coronary artery disease

ML O'Donoghue, DA Morrow, S Tsimikas… - Journal of the American …, 2014 - jacc.org
prevention are sparse and new lipid-modifying therapies that reduce Lp(a) are in development
(12–15), we assessed the independent prognostic utility of Lp(a) and evaluated proposed …

Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention

P Amarenco, J Labreuche - The Lancet Neurology, 2009 - thelancet.com
… Statin therapy has become the most important advance in stroke prevention since the
introduction of aspirin and blood pressure-lowering therapies. In combination with other preventive

Intensive low-density lipoprotein cholesterol lowering in cardiovascular disease prevention: opportunities and challenges

C Packard, MJ Chapman, M Sibartie, U Laufs… - Heart, 2021 - heart.bmj.com
Elevated levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased
risk of coronary heart disease and stroke. Guidelines for the management of dyslipidaemia …

[HTML][HTML] The importance of low-density lipoprotein cholesterol measurement and control as performance measures: a joint clinical perspective from the National Lipid …

SS Virani, K Aspry, DL Dixon, KC Ferdinand… - Journal of Clinical …, 2023 - Elsevier
prevention was <100 mg/dL, the NCQA set its new HEDIS performance metric as the percentage
of secondary prevention … dL) versus a performance measure for evaluating the care of a …

Treatment and prevention of lipoprotein (a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics

DI Swerdlow, DA Rider, A Yavari… - Cardiovascular …, 2022 - academic.oup.com
… In this review, we evaluate the causal role of Lp(a) across the cardiovascular disease spectrum,
examine the role of established lipid-modifying therapies in lowering Lp(a), and focus on …

Promise of low-density lipoprotein–lowering therapy for primary and secondary prevention

SM Grundy - Circulation, 2008 - Am Heart Assoc
… ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring
by computed tomography in global cardiovascular risk assessment and in evaluation of …