… diabetes. It is apparent that a number of different mechanisms of β cell destruction are operative
in type 1 diabetes. … protect β cells from destruction and thereby prevent type 1 diabetes. …

… from developing a pill to prevent type 1 diabetes, but all the … patients with type 1 diabetes:
the first is to prevent initiation of … Although highly ambitious, the prevention of type 1 diabetes …

… of type 1 diabetes. The goal of this study was to utilize data from the Diabetes Prevention
Trial–Type 1 (DPT-1) to obtain a picture of the metabolic progression to type 1 diabetes over a …

… DPT-1 cohorts to examine the prediction of type 1 diabetes by … have examined the prediction
of type 1 diabetes by a variety of … developed type 1 diabetes. One cohort includes DPT-…

Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity, …

… accurate prediction of type 1 diabetes is essential for appropriately identifying prevention
trial participants. Thus, we have developed a risk score for the prediction of type 1 diabetes. …

… Major research efforts are needed to achieve early diagnosis, prevent β-cell loss and
develop better treatment options to improve the quality of life and prognosis of those affected. …

… In the nonobese diabetic mouse model of type 1 diabetes, oral administration ofin~ sulin
to young, pre-diabetic mice inhibits their development of type 1 diabetes (813). Oral insulin …

… prevent type 1 diabetes in humans. More than 100 different treatments prevent type 1 diabetes
in the NOD mouse model, and this may indicate that disease prevention in this model is “…

… The results of the randomized clinical trials designed to delay or prevent type 1 diabetes
progression to date have indicated that timing of intervention, dosing and frequency, age at …