… Here, we review the main clinical aspects and the molecular basis of primary C3 deficiency
as … in secondary C3 deficiencies. We also discuss the use of animal models to study these …

… (PAD) are the most common subtype of primary immunodeficiencies, characterized by … to
selective Ig deficiency. In this study, we describe the molecular and the clinical aspects of fifty-…

… The great majority of patients with primary immuno-deficiency with autosomal recessive
inheritance are homozygous or compound heterozygous for the underlying genetic lesion, and …

… of patients with Cl-INH deficiency and two primary candidates still remain: bradykinin (BK) (…
yet been available for trials in Cl-INH deficiency. To provide indirect proof that BK participates …

… This systematic review focuses on the clinical aspects of primary antibody deficiencies,
including management and complications of primary antibody deficiencies in particular. …

Primary immunodeficiencies comprise a large group of diverse disorders. Figure 1 schematically
depicts antibody defects caused by inherent B lymphocyte abnormalities, as well as …

… Clinical manifestations of cobalamin deficiency The primary clinical manifestations of cobalamin
deficiency in elderly patients are described in Table 5. They are highly polymorphic and …

… Ελάχιστα από τα εν λόγω σύνδρομα των πρωτοπαθών ανοσοανεπαρκειών (primary … των
ασθενών με πρωτοπαθείς αντισωματικές ανεπάρκειες (primary antibody deficiencies, PADs) είτε …

In 100 hospitalized older patients with iron-deficiency anemia, the mean corpuscular
hemoglobin concentration (MCHC) varied with the degree of anemia, but the degree of …

… Primary antibody deficiencies are the most common primary immunodeficiency diseases.
They are a heterogeneous group of disorders with various degrees of dysfunctional antibody …