HPV for cervical cancer screening (HPV FOCAL): Complete Round 1 results of a randomized trial comparing HPV‐based primary screening to liquid‐based cytology …

GS Ogilvie, M Krajden, D van Niekerk… - … journal of cancer, 2017 - Wiley Online Library
HPV FOCAL, a randomized trial establishing the efficacy of HPV DNA testing with cytology
triage as a primary … with HPV testing; Intervention and Safety arms – Baseline HPV with LBC …

… screening with primary cervical HPV testing vs cytology testing on high-grade cervical intraepithelial neoplasia at 48 months: the HPV FOCAL randomized clinical trial

GS Ogilvie, D van Niekerk, M Krajden, LW Smith… - Jama, 2018 - jamanetwork.com
… The primary objective of this study was to evaluate primary HPV testing for cervical cancer
screening in an organized program setting. Ethics approval was obtained from the University …

[HTML][HTML] Primary cervical cancer screening with HPV testing compared with liquid-based cytology: results of round 1 of a randomised controlled trial–the HPV FOCAL …

GS Ogilvie, M Krajden, DJ Van Niekerk… - British journal of …, 2012 - nature.com
… for over 18 000 women of a primary HPV screening trial based within an organised cervical
screening programme in Canada are presented. At baseline screening, the CIN2+ detection …

[HTML][HTML] A randomized controlled trial of H uman P apilloma v irus (HPV) testing fo rc ervic al cancer screening: trial design and preliminary results (HPV FOCAL Trial)

GS Ogilvie, DJ van Niekerk, M Krajden, RE Martin… - BMC cancer, 2010 - Springer
… In the HPV FOCAL trial, we will establish the efficacy of hr-HPV DNA testing as a stand-…
preliminary screening results of the HPV FOCAL Trial. The primary objective of the HPV FOCAL

Assessing 10-year safety of a single negative HPV test for cervical cancer screening: evidence from FOCAL-DECADE cohort

A Gottschlich, D van Niekerk, LW Smith… - … Biomarkers & Prevention, 2021 - AACR
FOCAL participants for up to 10 years after trial baseline by linking FOCAL data to data from
the provincial screening … single negative primary HPV test for cervix screening by assessing …

Cost‐effectiveness analysis of primary human papillomavirus testing in cervical cancer screening: Results from the HPV FOCAL Trial

I Cromwell, LW Smith, K van Der Hoek… - Cancer …, 2021 - Wiley Online Library
… , HPV testing, and LBC testing. The HPV FOCAL Trial results suggest that primary HPV
outcomes to LBC-based testing every 2 years for cervical cancer screening at a lower cost. …

[PDF][PDF] Recommendations for implementing human Papillomavirus-Based cervical cancer screening: lessons learned from the HPV focal trial

L Smith, D van Niekerk, A Coldman… - J Obstet Gynaecol …, 2016 - bccancer.bc.ca
… The HPV FOCAL trial is a publicly funded clinical trial, conducted in British Columbia, that
is comparing primary HPV testing with liquid-based cytology for cervical cancer screening.…

Human papillomavirus‐based screening at extended intervals missed fewer cervical precancers than cytology in the HPV for Cervical Cancer (HPV FOCAL) trial

A Gottschlich, L Gondara, LW Smith… - … journal of cancer, 2022 - Wiley Online Library
… The objective of this analysis is to obtain evidence that could reassure programs
adopting primary HPV-based screening that the extended interval recommended with an …

[HTML][HTML] Aptima HPV Assay versus Hybrid Capture® 2 HPV test for primary cervical cancer screening in the HPV FOCAL trial

DA Cook, LW Smith, J Law, W Mei… - Journal of Clinical …, 2017 - Elsevier
… For AHPV positive women, both high-grade reflex LBC and HPV 16 infection were … for primary
screening together with colposcopy referral based on abnormal reflex cytology and HPV 16…

Women's acceptability of and experience with primary human papillomavirus testing for cervix screening: HPV FOCAL trial cross-sectional online survey results

LW Smith, CS Racey, L Gondara, M Krajden, M Lee… - BMJ open, 2021 - bmjopen.bmj.com
HPV FOCAL is currently the only North American trial comparing primary HPV testing to
cytology (liquid based) for screeningHPV testing in a population-based programme setting. The …