… The complete amino acid sequence of bovine bone matrix Gla protein (MGP) was determined
by automatic sequence analysis of the intact protein and of peptides isolated from tryptic …

… Matrix GLA protein (MGP) has been identified as a calcification inhibitor in cartilage and
vasculature. Part of this effect may be attributed to its influence on osteoinductive activity of bone …

… Vitamin K-dependent matrix Gla protein (MGP) has been suggested to play a role in the
inhibition of softtissue calcification. Here we report the expression of recombinant prokaryotic …

… site for the gamma-carboxylase. This four-exon organization is essentially identical to that of
bone Gla protein … the other known vitamin K-dependent proteins. Analysis of the MGP gene …

… The most striking of these mouse models is the matrix Gla protein (MGP) knockout mouse,
indicating that this protein may be of primary importance in human vascular calcification. The …

… Matrix Gla protein (MGP), a low molecular weight protein found in bone, dentin, and cartilage,
contains 5 residues of the vitamin K-dependent amino acid y-carboxyglutamic acid (Gla). …

… -kD skeletal extracellular matrix (ECM) protein that consists of an 84-aa mature protein and a
… of the Gla protein family, which includes osteocalcin 6 , another skeletal ECM protein, and a …

… Inactivation of Matrix gla protein (Mgp) revealed that MGP is an inhibitor of ECMM. The
fact that MGP is present in the general circulation raises the question of whether ECMM is …

… It is the result of an active ossification process counteracted by ‘protective’ proteins, such
as matrix GLA protein (MGP). Polymorphisms of MGP have been identified. Methods: The aim …

… Matrix Gla protein, an essential Ca 2+ chelator that prevents vascular calcification, was …
SDS-PAGE under denaturing conditions. The mass of the folded matrix Gla protein as measured …