Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy

J Xie, G Liu, HS Eden, H Ai, X Chen - Accounts of chemical …, 2011 - ACS Publications
… of functionalities, such as targeting, imaging and therapeutic features, onto their surfaces. …
affect the role of nanoparticles as imaging or therapeutic agents. We and others have …

Target ablation—image-guided therapy in prostate cancer

A Marien, I Gill, O Ukimura, B Nacim, A Villers - Urologic oncology: seminars …, 2014 - Elsevier
… There has been a demand to develop ablative therapies that attempt to reduce treatment …
We reviewed the literature to concentrate on the practical aspects of focal therapy for Pca …

Applications of pHLIP technology for cancer imaging and therapy

LC Wyatt, JS Lewis, OA Andreev, YK Reshetnyak… - Trends in …, 2017 - cell.com
… pHLIP ® s target cancer cells in primary tumors as well as metastases based on the acidic
… Peptides of the pHLIP family share the same features in their primary sequences (Figure I) …

[HTML][HTML] Pretargeting in nuclear imaging and radionuclide therapy: Improving efficacy of theranostics and nanomedicines

EJL Stéen, PE Edem, K Nørregaard, JT Jørgensen… - Biomaterials, 2018 - Elsevier
… with primary or metastatic liver cancer. In phase I/II clinical trials, they found that the
treatment efficacy was low. Detailed imaging analysis revealed retrospectively that PK2 targets

Nanomedicine for drug delivery and imaging: a promising avenue for cancer therapy and diagnosis using targeted functional nanoparticles

Y Liu, H Miyoshi, M Nakamura - International journal of cancer, 2007 - Wiley Online Library
… Because of the size and supramolecular structure of nanoparticle, technologies utilizing
nanoparticles have much potential for improving cancer therapy. A primary attribute of …

HER2 monoclonal antibody conjugated RNase-A-associated CdTe quantum dots for targeted imaging and therapy of gastric cancer

J Ruan, H Song, Q Qian, C Li, K Wang, C Bao, D Cui - Biomaterials, 2012 - Elsevier
Successful development of safe and effective nanoprobes for targeted imaging and selective
therapy of in-situ gastric cancer is a great challenge. Herein, one kind of multifunctional …

CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma

L Wang, W Su, Z Liu, M Zhou, S Chen, Y Chen, D Lu… - Biomaterials, 2012 - Elsevier
Most hepatocellular carcinoma (HCC) therapies fail to targetimaging and simultaneously
monitoring targeted therapy in a … tumor model was applied for therapy by injecting 1.0 × 10 6 …

Norepinephrine transporter as a target for imaging and therapy

N Pandit-Taskar, S Modak - Journal of Nuclear Medicine, 2017 - Soc Nuclear Med
… In neuroendocrine tumors, NET can be targeted for imaging as well as therapy. One of the
most widely used theranostic agents targeting NET is metaiodobenzylguanidine (MIBG), a …

Vascular targeted therapy with anti–prostate-specific membrane antigen monoclonal antibody J591 in advanced solid tumors

MI Milowsky, DM Nanus, L Kostakoglu… - Journal of Clinical …, 2007 - ascopubs.org
… This was a proof-of-principle evaluation of PSMA as a potential neovascular target. The
primary end points were targeting,toxicity, maximum-tolerated dose, pharmacokinetics (PK), and …

Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods

RM Sharkey, H Karacay, TM Cardillo, CH Chang… - Clinical cancer …, 2005 - AACR
… A commonly held belief for all pretargeting procedures is that the primary targeting agent …
primary targeting agent than would be required to saturate the target antigen in most tumors. …