Improving the delivery of radionuclides for imaging and therapy of cancer using pretargeting methods

RM Sharkey, H Karacay, TM Cardillo, CH Chang… - Clinical cancer …, 2005 - AACR
… A commonly held belief for all pretargeting procedures is that the primary targeting agent …
primary targeting agent than would be required to saturate the target antigen in most tumors. …

Somatostatin Receptor‐Based Molecular Imaging and Therapy for Neuroendocrine Tumors

L Wang, K Tang, Q Zhang, H Li, Z Wen… - BioMed research …, 2013 - Wiley Online Library
… The overexpression of SSTR is a characteristic of NETs, which can be used to localize
the primary tumor and its metastases by imaging with the radiolabeled SST analogues [19]. …

Radiolabeled antibodies for cancer imaging and therapy

J Barbet, M Bardiès, M Bourgeois, JF Chatal… - … : Methods and Protocols …, 2012 - Springer
Radiolabeled antibodies were studied first for tumor detection by single-photon imaging, but
FDG PET stopped these developments. In the meantime, radiolabeled antibodies were …

Shiga toxin and its use in targeted cancer therapy and imaging

N Engedal, T Skotland, ML Torgersen… - Microbial …, 2011 - Wiley Online Library
… Stx binds specifically to the glycosphingolipid globotriaosylceramide (Gb3) at the surface of
target … to therapeutic compounds or contrast agents in targeted cancer therapy and imaging. …

Recent advances in transarterial therapy of primary and secondary liver malignancies

SP Kalva, A Thabet, S Wicky - Radiographics, 2008 - pubs.rsna.org
… Few patients with primary hepatocellular carcinoma or metastatic … therapeutic option.
Because the hepatic tumor burden is often a determinant of eligibility for surgery and is a primary

Peptides and receptors in image-guided therapy: theranostics for neuroendocrine neoplasms

RP Baum, HR Kulkarni, C Carreras - Seminars in nuclear medicine, 2012 - Elsevier
imaging (CI) modalities like ultrasound, endoscopy, CT scan, and magnetic resonance
imaging (MRI) for detecting the site of the primary … or tissues/cells are targeted to explore every …

Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past years…

[HTML][HTML] The role of image-guided therapy in the management of colorectal cancer metastatic disease

T de Baere, L Tselikas, S Yevich, V Boige… - European Journal of …, 2017 - Elsevier
… , number of metastases >3 and location of primary disease other than colon or kidney. In the
… lung metastasectomy, which include location of the primary disease, number of metastases, …

Targeting of activated fibroblasts for imaging and therapy

T Lindner, A Loktev, F Giesel, C Kratochwil… - EJNMMI radiopharmacy …, 2019 - Springer
… development of therapy resistance, they represent excellent target cells for antitumor therapy.
… This strategy led to a CD8+ T cell-mediated killing the fibroblasts, suppression of primary

Stage IV breast cancer in the era of targeted therapy: does surgery of the primary tumor matter?

HB Neuman, M Morrogh, M Gonen… - … Journal of the …, 2010 - Wiley Online Library
primary tumor in patients presenting with stage IV disease in the era of molecularly targeted
therapy… from primary tumor treatment and assess the frequency of local disease progression. …