Indole: A privileged scaffold for the design of anti-cancer agents

Y Wan, Y Li, C Yan, M Yan, Z Tang - European journal of medicinal …, 2019 - Elsevier
anti-cancer agents. In view of its unique physic-chemical and biological properties, it has been
used as a privileged scaffold in the anti-cancer agents … promising anti-cancer agents used …

An overview of privileged scaffold: quinolines and isoquinolines in medicinal chemistry as anticancer agents

Y Mao, K Soni, C Sangani, Y Yao - Current Topics in Medicinal …, 2020 - ingentaconnect.com
… an antitumor agent in anticancer treatment. The members of this privileged scaffold quinoline
… of quinoline and isoquinoline derivatives as antitumor agents and refine the path of these …

Pyridazine based scaffolds as privileged structures in anti-cancer therapy

MY Jaballah, RT Serya, K Abouzid - Drug Research, 2017 - thieme-connect.com
… In this regard the study of transition metal-based anticancer agents remains an area of
intense research activity [25]. The covalent modification of DNA is a classical strategy, as …

Chromones: Privileged scaffold in anticancer drug discovery

VM Patil, N Masand, S Verma… - Chemical Biology & …, 2021 - Wiley Online Library
… In the past few decades, literature reports investigation of chromones as anticancer agents
against a variety of molecular targets namely, protein kinases, protein tyrosine phosphatases, …

Tetrazole: A privileged scaffold for the discovery of anticancer agents

A Verma, B Kaur, S Venugopal… - Chemical Biology & …, 2022 - Wiley Online Library
… Currently, several anticancer agents are commercially available in the global market. … more
interest in developing newer novel potential anticancer agents. In the search for new drugs …

Thiazolidinedione: A privileged scaffold for the development of anticancer agents

J Sun, YH Chen, HY Liu, E Hondo… - Current Topics in …, 2021 - ingentaconnect.com
privileged and promising scaffold in the field of medicinal chemistry along with its anticancer
… of new thiazolidinedione derivatives as anticancer agents. Furthermore, in the same search …

An overview of quinoline as a privileged scaffold in cancer drug discovery

R Musiol - Expert Opinion on Drug Discovery, 2017 - Taylor & Francis
… Increasing interest in quinoline-based anticancer agentsagents. With these in mind,
quinoline will remain an essential structural motif in anticancer agents – a real privileged scaffold. …

Quinoline as a privileged scaffold in cancer drug discovery

VR Solomon, H Lee - Current medicinal chemistry, 2011 - ingentaconnect.com
… inhibitor of EGFR, it is currently being developed as an effective anticancer agent [21]. …
inhibitors of Src are being actively investigated as potential anticancer agents [74-76]. Using a …

Roles of pyridine and pyrimidine derivatives as privileged scaffolds in anticancer agents

S Prachayasittikul, R Pingaew… - Mini Reviews in …, 2017 - ingentaconnect.com
… of these small molecules as privileged scaffolds with attractive properties and biological
activities for the search of novel anticancer agents. Keywords: Anticancer agents, cancer, fused-…

2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents

Y Wan, J Long, H Gao, Z Tang - European Journal of Medicinal Chemistry, 2021 - Elsevier
… of 2-aminothiazole as a privileged scaffold in anti-cancer agents discovery. In addition, …
anti-cancer agents are also probed to offer an insight to design more effective anti-cancer agents