Novel targeted pro-apoptotic agents for the treatment of prostate cancer

X Huang, X Zhang, B Farahvash, AF Olumi - The Journal of urology, 2007 - Elsevier
… selected patients with prostate cancer and other malignancies. Because neoadjuvant and
adjuvant clinical trials are under way using novel pro-apoptotic agents for prostate cancer, it is …

Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells

M Rivera, Y Ramos, M Rodriguez-Valentin… - PLoS …, 2017 - journals.plos.org
… Chronic ER stress induction was concomitant with the upregulation of pro-apoptotic markers
… anti-tumor markers, supporting their curcumin-induced pro-apoptotic role in prostate cancer

miR‐125b promotes growth of prostate cancer xenograft tumor through targeting proapoptotic genes

XB Shi, L Xue, AH Ma, CG Tepper, HJ Kung… - … Prostate, 2011 - Wiley Online Library
… are pro-apoptotic molecules, our results show that miR-125b is involved in the p53 network
and plays a role … suppression of miR-125b can inhibit tumor growth. In addition to these three …

Growth inhibitory, antiandrogenic, and pro-apoptotic effects of punicic acid in LNCaP human prostate cancer cells

J Gasmi, JT Sanderson - Journal of agricultural and food chemistry, 2010 - ACS Publications
Prostate cancer is a commonly diagnosed cancer in men, … pro-apoptotic effects of 13 pure
compounds found in the pomegranate in androgen-dependent LNCaP human prostate cancer

Apoptosis in prostate cancer: progressive and therapeutic implications

G Wang, E Reed, QQ Li - International journal of …, 2004 - spandidos-publications.com
… to prostate cancer progression. We focus on some key regulatory molecules, including the
pro-apoptotic … roles in prostate cancer progression and their therapeutic implications in human …

Pro-apoptotic effect of aurothiomalate in prostate cancer cells

M Trani, A Sorrentino, C Busch, M Landström - Cell Cycle, 2009 - Taylor & Francis
prostate cancer cells in vitro (our unpublished data). Here, we report that ATM has a pro-apoptotic
effect in prostate cancer cells without affecting the viability of normal epithelial prostate

Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer

M Shiota, A Yokomizo, S Naito - Endocrine-related cancer, 2012 - erc.bioscientifica.com
… effects in prostate cancer cells in response to androgen deprivation therapy. In addition,
AR signaling suppresses anti-survival and pro-apoptotic effects in prostate cancer cells in …

Pro-apoptotic tumor necrosis factor-α transduction pathway in normal prostate, benign prostatic hyperplasia and prostatic carcinoma

M Ricote, M Royuela, I Garcia-Tunon… - The Journal of …, 2003 - Elsevier
… In prostate cancer this pathway is probably inactivated by other factors, such as p21 (at the
… -α and its receptors in benign prostatic hyperplasia (BPH) and prostatic carcinoma (PC) has …

Oligomeric proanthocyanidin complexes (OPC) exert anti‐proliferative and proapoptotic effects on prostate cancer cells

H Neuwirt, MC Arias, M Puhr, A Hobisch, Z Culig - The Prostate, 2008 - Wiley Online Library
… In the present study, we show that OPC has an antiproliferative and pro-apoptotic effect in
three prostate cancer cell lines. We showed that AR expression in LNCaP cells is reduced by …

Potent Anti-Proliferative, Pro-Apoptotic Activity of the Maytenus Royleanus Extract against Prostate Cancer Cells: Evidence in In-Vitro and In-Vivo Models

M Shabbir, DN Syed, RK Lall, MR Khan, H Mukhtar - PloS one, 2015 - journals.plos.org
… Here, we studied the effect of MEM on prostate cancer cell … prostate cancer cells and
exerts potent inhibitory effect on AR/PSA signaling both in in vitro cell cultures and in vivo tumor