Delivering proangiogenic factors from 3D‐printed polycaprolactone scaffolds for vascularized bone regeneration

H Liu, Y Du, G Yang, X Hu, L Wang… - Advanced …, 2020 - Wiley Online Library
… ) derived scaffold, with an angiogenic growth factor immobilized … porous
polycaprolactone/hydroxyapatite (PCL/HA) scaffold is … factor (VEGF) by coprecipitation with …

Accelerating vascularization in polycaprolactone scaffolds by endothelial progenitor cells

S Singh, BM Wu, JCY Dunn - Tissue Engineering Part A, 2011 - liebertpub.com
polycaprolactone (PCL) scaffolds by the delivery of endothelial progenitor cells (EPCs).
To establish a pro-angiogenic … employed EPCs seeded in PCL scaffold with surface-immobilized …

Dual drug-delivering polycaprolactone-collagen scaffold to induce early osteogenic differentiation and coupled angiogenesis

HA Rather, R Patel, UCS Yadav, R Vasita - Biomedical Materials, 2020 - iopscience.iop.org
polycaprolactone-collagen fibrous scaffold is reported to promote early osteogenesis and
angiogenesis. Simvastatin as a pro-angiogenicpro-angiogenic drug promotes angiogenesis. …

Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic …

RP Tan, AHP Chan, K Lennartsson, MM Miravet… - Stem cell research & …, 2018 - Springer
… Using these scaffolds as engraftment platforms, we assess their potential to augment the
proangiogenic effects of iPSC-ECs following implantation in vivo. Through gene expression …

Polylactide-and polycaprolactone-based substrates enhance angiogenic potential of human umbilical cord-derived mesenchymal stem cells in vitro-implications for …

M Sekuła, P Domalik-Pyzik… - Materials Science and …, 2017 - Elsevier
… regenerative capacity including migratory and proangiogenic potential, which are required
for effective vascular repair in vivo. Thus, PLA and PCL-based scaffolds combined with hUC-…

The enhancement of VEGF-mediated angiogenesis by polycaprolactone scaffolds with surface cross-linked heparin

S Singh, BM Wu, JCY Dunn - Biomaterials, 2011 - Elsevier
factors. Although various strategies have been devised to deliver pro-angiogenic growth factors,
… [4], the problem of inadequate blood vessels within scaffolds remains at large. Even with …

Investigation of angiogenesis and its mechanism using zinc oxide nanoparticle-loaded electrospun tissue engineering scaffolds

R Augustine, EA Dominic, I Reju, B Kaimal… - Rsc Advances, 2014 - pubs.rsc.org
factor mediated mechanisms. Here, we report the fabrication of electrospun polycaprolactone
scaffolds … by the expression of key proangiogenic factors, fibroblast growth factor (FGF) and …

Polycaprolactone nanofibers containing vascular endothelial growth factor-encapsulated gelatin particles enhance mesenchymal stem cell differentiation and …

YC Jiang, XF Wang, YY Xu, YH Qiao, X Guo… - …, 2018 - ACS Publications
scaffold platform, consisting of polycaprolactone (PCL) nanofibers and vascular endothelial
growth factor (… The results showed that this kind of scaffold can direct the differentiation of …

Crosstalk between osteoblasts and endothelial cells co-cultured on a polycaprolactone–starch scaffold and the in vitro development of vascularization

MI Santos, RE Unger, RA Sousa, RL Reis… - Biomaterials, 2009 - Elsevier
… between ECs and osteoblast cells occurs via diffusible factors as well as direct cell–cell …
the soluble factor examined in this study since it is a powerful pro-angiogenic factor with well …

Poly-ε-caprolactone/fibrin-alginate scaffold: a new pro-angiogenic composite biomaterial for the treatment of bone defects

J Ren, N Kohli, V Sharma, T Shakouri… - Polymers, 2021 - mdpi.com
… , resorbable PCL scaffold would provide a novel superior composite scaffold that facilitates
… a pro-angiogenic fibrin-based biomaterial component (fibrin/alginate) as part of the scaffold