Bioavailability of curcumin: problems and promises

P Anand, AB Kunnumakkara, RA Newman… - Molecular …, 2007 - ACS Publications
… and excretion of curcumin have revealed poor absorption and rapid metabolism of curcumin
that severely curtails its bioavailability. In this section, problems of curcumin bioavailability

[HTML][HTML] Improving curcumin bioavailability: Current strategies and future perspectives

R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
… for enhancing curcumin bioavailability, considering the technologies used and clinical trials
that prove the effectiveness of the methods. Curcumin holds great promise in clinical practice …

Oral bioavailability of curcumin: problems and advancements

W Liu, Y Zhai, X Heng, FY Che, W Chen… - Journal of drug …, 2016 - Taylor & Francis
… offer significant promise and are worthy of further exploration in attempt to enhance the …
bioavailability of curcumin. This review mainly describes the problem of low oral bioavailability

Is curcumin bioavailability a problem in humans: Lessons from clinical trials

AB Kunnumakkara, C Harsha, K Banik… - Expert opinion on …, 2019 - Taylor & Francis
curcumin, as demonstrated by clinical trials has overpowered the myth that poor bioavailability
of curcumin poses a problem… In summary, poor bioavailability of curcumin is not a problem

[HTML][HTML] The problem of curcumin and its bioavailability: could its gastrointestinal influence contribute to its overall health-enhancing effects?

AL Lopresti - Advances in Nutrition, 2018 - Elsevier
… therefore holds promise as a … curcumin's clinical efficacy is its poor bioavailability. Efforts
have therefore been dedicated to developing curcumin formulations with greater bioavailability

[HTML][HTML] The holy grail of curcumin and its efficacy in various diseases: is bioavailability truly a big concern?

S Toden, A Goel - Journal of restorative medicine, 2017 - ncbi.nlm.nih.gov
… forward we must recognize that bioavailability of curcumin should not be the sole focus,
but we should consider absorption and bioavailability of both curcumin and its metabolites to …

[HTML][HTML] Obstacles against the Marketing of Curcumin as a Drug

K Hassanzadeh, L Buccarello, J Dragotto… - International journal of …, 2020 - mdpi.com
… , micro-emulsions, or polymer micelles suggest significant promise and are worthy of further
investigation to enhance the oral bioavailability of curcumin. Here we reviewed some new …

Can improving bioavailability improve the bioactivity of curcumin?

HF Ji, L Shen - Trends in pharmacological sciences, 2014 - cell.com
… Here, we attempt to explain the reason that enhanced bioavailability of curcumin is not
associated with improved pharmacological efficacy. It has been proven that curcumin possesses …

[PDF][PDF] Curcumin therapeutic promises and bioavailability in colorectal cancer

A Shehzad, S Khan, O Shehzad, YS Lee - Drugs of today, 2010 - academia.edu
curcumin treatment in colorectal cancers were also cited, to shed light on the importance of
curcumin … vivo evidences and factors controlling curcumin bioavailability, as well as different …

Systemic delivery of curcumin: 21st century solutions for an ancient conundrum

S Bisht, A Maitra - Current drug discovery technologies, 2009 - ingentaconnect.com
… and phospholipid complex formulations of curcumin. This review is intended to provide the
reader an update on the bioavailability and pharmacokinetic pitfalls of free curcumin, and a …