Recent developments in formulation design for improving oral bioavailability of curcumin: a review

Z Liu, JD Smart, AS Pannala - Journal of drug delivery science and …, 2020 - Elsevier
… To overcome curcumin's problem of bioavailability, … bioavailability of curcumin are first
explained in detail followed by a review of recent efforts in improving curcumin's oral bioavailability

An update on the pharmacological usage of curcumin: has it failed in the drug discovery pipeline?

F Olotu, C Agoni, O Soremekun… - Cell Biochemistry and …, 2020 - Springer
… to poor oral bioavailability. Also, we highlight strategies that have been developed to …
curcumin bioavailability and efficacy in various disease models. This enumerates novel curcumin

A short review on chemical properties, stability and nano-technological advances for curcumin delivery

L Slika, D Patra - Expert opinion on drug delivery, 2020 - Taylor & Francis
… that curcumin suffers from bioavailability problems such as low … properties of curcumin, its
stability, bioavailability problems, … with special highlight on nanocapsules for curcumin delivery. …

[PDF][PDF] Curcumin, the panacea: A review on advancement to solve pharmaco-kinetic problems.

N Mor, N Raghav - Chemistry & Biology Interface, 2021 - researchgate.net
… Although curcumin displays various pharmacological activities, it has limited bioavailability
… to bioavailability of curcumin related pharmacokinetic problems and concurrent solutions. …

[PDF][PDF] Progress and problems in nutraceuticals delivery

NM Zaki - Journal of Bioequivalence & Bioavailability, 2014 - researchgate.net
… The best characterized polyphenol member is Curcumin & its … of apoptosis signaling (curcumin
inhibits Bcl2 and activates … a satisfactory bioavailability for such nutraceuticals. The …

Enhancing curcumin oral bioavailability through nanoformulations

VS Ipar, A Dsouza, PV Devarajan - European journal of drug metabolism …, 2019 - Springer
… As well as being a substrate of P-gp, curcumin binds to multidrug resistance-associated …
low bioavailability [33, 34]. All of these factors synergistically limit the bioavailability of curcumin. …

Conundrum and therapeutic potential of curcumin in drug delivery

A Kumar, A Ahuja, J Ali… - Critical Reviews™ in …, 2010 - dl.begellhouse.com
… Tissue targeting and enhanced bioavailability of curcumin using novel drug-delivery … in
the field of curcumin drug delivery with special emphasis on bioavailability-enhancement …

Nanostructures for curcumin delivery: possibilities and challenges

PA Subramani, K Panati, VR Lebaka, DD Reddy… - Nano-and Microscale …, 2017 - Elsevier
bioavailability of curcumin. In this chapter, we review the potential antimicrobial activity of
curcumin, its oral bioavailability … researchers so far to overcome this problem. Finally, we would …

[PDF][PDF] Curcumin nanoforms promise better therapeutic values

H Rachmawati - Int. J. Res. Pharm. Sci, 2013 - researchgate.net
… On top of that, nano-enabled drug delivery systems show good promise in overcoming the
problem of low bioavailability of curcumin (figure 2). In order to assess nano-based curcumin's

Dietary curcumin: correlation between bioavailability and health potential

M Dei Cas, R Ghidoni - Nutrients, 2019 - mdpi.com
… potential of curcumin is indeed still debated due to a relatively poor bioavailability in humans,
… Generally, the oral bioavailability of curcumin is low due to a relatively low absorption by …