From flavors and pharmaceuticals to advanced biofuels: Production of isoprenoids in Saccharomyces cerevisiae

S Tippmann, Y Chen, V Siewers… - Biotechnology …, 2013 - Wiley Online Library
… of isoprenoid applications … Saccharomyces cerevisiae for the production of these compounds.
While the high complexity of biosynthetic pathways and the toxicity of certain isoprenoids

Metabolic engineering and synthetic biology for isoprenoid production in Escherichia coli and Saccharomyces cerevisiae

GR Navale, MS Dharne, SS Shinde - Applied Microbiology and …, 2021 - Springer
production of these isoprenoids in the heterologous host systems like Escherichia coli and
Saccharomyces cerevisiae… for large-scale production of value-added isoprenoids. This review …

Recent advances in the biosynthesis of isoprenoids in engineered Saccharomyces cerevisiae

Z Wang, R Zhang, Q Yang, J Zhang, Y Zhao… - Advances in Applied …, 2021 - Elsevier
… and efficient production of valuable isoprenoids on … , Saccharomyces cerevisiae has become
an attractive microbial host for biochemical production, including that of various isoprenoids

Engineering Saccharomyces cerevisiae for isoprenol production

J Kim, EEK Baidoo, B Amer, A Mukhopadhyay… - Metabolic …, 2021 - Elsevier
Saccharomyces cerevisiae has been widely used in the biotechnology industry for isoprenoid
production, but there has been no good example of isoprenol production reported in this …

Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae

JA Chemler, Y Yan, MAG Koffas - Microbial Cell Factories, 2006 - Springer
… of microorganisms for the production of synthetic chemicals or … pathways into Saccharomyces
cerevisiae have greatly … cerevisiae for their production is only expected to expand in …

… isoprene production by reconstruction of metabolic balance between strengthened precursor supply and improved isoprene synthase in Saccharomyces cerevisiae

Z Yao, P Zhou, B Su, S Su, L Ye, H Yu - ACS Synthetic Biology, 2018 - ACS Publications
… (1−4) Recently, as high as 24 g/L of isoprene production was achieved in E. coli by building
synergy between the two isoprenoid precursor pathways, MVA pathway and methylerythritol …

Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids

Y Shiba, EM Paradise, J Kirby, DK Ro… - Metabolic engineering, 2007 - Elsevier
cerevisiae. Overproduction of acetaldehyde dehydrogenase and introduction of a … production.
This work will be generally applicable to the production of a broad range of isoprenoids in …

Modification of isoprene synthesis to enable production of curcurbitadienol synthesis in Saccharomyces cerevisiae

J Qiao, Z Luo, S Cui, H Zhao, Q Tang… - Journal of Industrial …, 2019 - academic.oup.com
… As an alternative production strategy, we developed baker’s yeast Saccharomyces cerevisiae
as a … Improving supplies of isoprenoid precursors was then investigated for increasing …

Enhanced isoprenoid production from xylose by engineered Saccharomyces cerevisiae

S Kwak, SR Kim, H Xu, GC Zhang… - Biotechnology and …, 2017 - Wiley Online Library
… by engineered yeast for producing isoprenoids, we chose two isoprenoids: squalene and …
intracellular isoprenoids, and amorphadiene is heterologous and diffusible isoprenoids. We …

Microbial production of isoprenoids

SS Chandran, JT Kealey, CD Reeves - Process biochemistry, 2011 - Elsevier
… coli, and the HMG-CoA synthase (HMGS) and truncated HMG-CoA reductase (tHMGR)
from Saccharomyces cerevisiae. The MBIS operon was made up of the mevalonate kinase (MK), …