Clinical and experimental investigation of aneurysmal subarachnoid hemorrhage

R Leblanc - Current Opinion in Neurology, 1991 - journals.lww.com
… and extending into the subarachnoid space (SAS), as … products in the genesis of VSP has
been investigated. Peterson et al. [18] observed that cisternal injection of hemolysis products

Time-course of blood-brain barrier permeability changes after experimental subarachnoid haemorrhage

A Germano, D d'Avella, C Imperatore, G Caruso… - Acta …, 2000 - Springer
… SAH was induced in 56 rats by injection of blood into the subarachnoid space via the … that
free radical reactions, deriving from bloodbreakdown products, play a pivotal role in the patho…

[HTML][HTML] Impaired microcirculation after subarachnoid hemorrhage in an in vivo animal model

KC Wang, SC Tang, JE Lee, JC Tsai, DM Lai… - Scientific Reports, 2018 - nature.com
… (A) Red blood cells were seen in the subarachnoid space (arrowhead) in the rat SAH model.
Diffuse thrombosis of small vessels beneath the cortex (black arrow) was demonstrated by …

[HTML][HTML] Spreading depolarizations and subarachnoid hemorrhage

K Sugimoto, DY Chung - Neurotherapeutics, 2020 - Elsevier
… the subarachnoid space is much smaller than that of humans. Therefore, accumulation of
erythrocyte products in the subarachnoid space is less likely in small animals than in humans. …

Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage

ED Hall, JM McCall, ED Means - Advances in pharmacology, 1994 - Elsevier
… A follow-up study investigated the effect of tirilazad on the LP product, malonyldialdehyde
(a by-product of LP), in the subarachnoid clot (Kanamaru et al., 1991). Cynomolgus monkeys (…

Prognostic value of intrathecal heme oxygenase–1 concentration in patients with Fisher Grade III aneurysmal subarachnoid hemorrhage

KC Wang, SC Tang, JE Lee, DM Lai, SJ Huang… - Journal of …, 2014 - thejns.org
… occurrence of SAH, hemolysis of red blood cells in the subarachnoid space results in rapid
… oxidation products (BOXes) and their role in cerebral vasospasm after subarachnoid hem- …

[HTML][HTML] Update: microdialysis for monitoring cerebral metabolic dysfunction after subarachnoid hemorrhage

P Spencer, Y Jiang, N Liu, J Han, Y Li… - Journal of Clinical …, 2020 - mdpi.com
… rupture, blood enters the subarachnoid space, increasing ICP, … hemolysis of red blood cells
in subarachnoid space causes … Lactate is the major product of glycolysis and is linked to the …

Beyond delayed cerebral vasospasm: infarct patterns in patients with subarachnoid hemorrhage

M Wagner, P Steinbeis, E Güresir… - Clinical …, 2013 - search.proquest.com
Products of hemolysis in the subarachnoid space inducing spreading ischemia in the
cortex … neurological deficits after subarachnoid hemorrhage. J neurosurg. 2000;93:658–66. …

[HTML][HTML] Subarachnoid hemorrhage: management considerations for COVID-19

EJ Panther, B Lucke-Wold - Exploration of neuroprotective …, 2022 - explorationpub.com
… by the presence of blood in the subarachnoid space, brain parenchyma, and occasionally
… One possible explanation for post-SAH cerebral vasospasm is subarachnoid hemolysis

[HTML][HTML] Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury

Y Chen, I Galea, RL Macdonald, GKC Wong… - …, 2022 - thelancet.com
… bleeding into the subarachnoid space and hypoxia due to … products in CSF; at least two
types of materials should be specifically considered and monitored. One is haemolytic product-…