… as prognostic indicators in cancer is studied. In addition, therapeutic intervention of tumour
… of MMPs as prognostic markers and as targets for therapeutic intervention in cancer. © 2002 …

… be an attractive target for tumour therapy, due to its versatility, there is still much need for
development and thorough pre-clinical evaluation of a suitable therapeutic strategy in order to …

… prognostic markers … prognostic marker in several publicly available breast cancer datasets,
high expression of the lactic acidosis response signature was associated with good prognosis…

… are not commonly used as prognostic markers or in treatment stratification in … prognostic
markers. The combination of several MMPs or MMPs together with other prognostic markers …

… prognosis in patients non-seminomatous germ cell tumours, CA 125 for monitoring therapy
in … PAI-1 are potent and independent prognostic markers in breast cancer. Although not yet in …

… Other studies have demonstrated that plasma VEGF-A may serve as a prognostic marker,
but is unable to predict response to VEGF-targeted therapy in advanced CRC[94,95]. At the …

… The aim of the current study was to prospectively test the clinical validity of BCL2 as a
prognostic marker independent of ER, HER2 and adjuvant therapy received, in addition to tumour …

… Molecular markers could also be measured in surrogate tissue such as sera, allowing …
following tumour resection or their response to medical therapy. Finally, these molecular markers …

… prognostic marker must be a proven independent, significant factor, that is easy to
determine and interpret and has therapeutic … reporting tumour marker prognostic studies (REMARK). …

… Platinum-based chemotherapy is the therapeutic foundation of treatment both in the …
Defining predictive and prognostic markers A prognostic factor is a patient or tumour characteristic …