Zbtb20 defines a hippocampal neuronal identity through direct repression of genes that control projection neuron development in the isocortex
JV Nielsen, M Thomassen, K Møllgård… - Cerebral …, 2014 - academic.oup.com
… -layer projection neurons. Using a Zbtb20 gain-of-function mouse model, we show that these
TFs are repressed during the Zbtb20-mediated specification of CA1 pyramidal neurons. We …
TFs are repressed during the Zbtb20-mediated specification of CA1 pyramidal neurons. We …
The specification of cortical subcerebral projection neurons depends on the direct repression of TBR1 by CTIP1/BCL11a
J Cánovas, FA Berndt, H Sepúlveda… - Journal of …, 2015 - Soc Neuroscience
… On the basis of our results showing the repressive effect of CTIP1 on TBR1 expression and
the fact that layer 6 neurons exhibit lower CTIP1 expression and higher TBR1 expression …
the fact that layer 6 neurons exhibit lower CTIP1 expression and higher TBR1 expression …
The determination of projection neuron identity in the developing cerebral cortex
DP Leone, K Srinivasan, B Chen, E Alcamo… - Current opinion in …, 2008 - Elsevier
… that determine projection neuron identity during cortical development. Pyramidal neurons in
the … , it is conceivable that Sox5 may directly repress Ctip2 expression in subplate neurons. …
the … , it is conceivable that Sox5 may directly repress Ctip2 expression in subplate neurons. …
[HTML][HTML] Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons
… Tbr1 and Sox5 are both expressed at high levels in corticothalamic projection neurons.
They promote a corticothalamic neuronal fate and directly repress Fezf2 expression and …
They promote a corticothalamic neuronal fate and directly repress Fezf2 expression and …
A network of genetic repression and derepression specifies projection fates in the developing neocortex
K Srinivasan, DP Leone, RK Bateson… - Proceedings of the …, 2012 - National Acad Sciences
… To determine whether high levels of Bhlhb5 expression are sufficient to direct axons toward
… Our data suggest that cortical projection neurons actively repress alternate fates to promote …
… Our data suggest that cortical projection neurons actively repress alternate fates to promote …
Molecular logic of neocortical projection neuron specification, development and diversity
LC Greig, MB Woodworth, MJ Galazo… - Nature Reviews …, 2013 - nature.com
… -repression between genetic programmes driving the development of one subtype of projection
neuron … Here, we provide an integrative account of the molecular controls that direct the …
neuron … Here, we provide an integrative account of the molecular controls that direct the …
[HTML][HTML] Instructing perisomatic inhibition by direct lineage reprogramming of neocortical projection neurons
Z Ye, MA Mostajo-Radji, JR Brown, C Rouaux… - Neuron, 2015 - cell.com
… Whether the class-specific identity of projection neurons has a role in the establishment of
… that direct in vivo lineage reprogramming of layer 2/3 (L2/3) callosal projection neurons (…
… that direct in vivo lineage reprogramming of layer 2/3 (L2/3) callosal projection neurons (…
COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression
C Alfano, L Viola, JIT Heng, M Pirozzi… - …, 2011 - journals.biologists.com
… We show that COUP-TFI directly represses Rnd2 expression at the post-mitotic level along
… suggest a direct repression of Rnd2 by COUP-TFI in post-mitotic late-born cortical neurons. …
… suggest a direct repression of Rnd2 by COUP-TFI in post-mitotic late-born cortical neurons. …
[HTML][HTML] Sensory cortex wiring requires preselection of short-and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
PS Hou, G Miyoshi, C Hanashima - Nature communications, 2019 - nature.com
… projection neuron types in the sensory neocortex. Mechanistically, Foxg1 binds to an
H3K4me1-enriched enhancer site to repress … Our results demonstrated that the direct binding of …
H3K4me1-enriched enhancer site to repress … Our results demonstrated that the direct binding of …
Even-skipped, acting as a repressor, regulates axonal projections in Drosophila
M Fujioka, BC Lear, M Landgraf, GL Yusibova, J Zhou… - 2003 - journals.biologists.com
… was capable of actively repressing UAS target genes in these neurons. A key target of the
… a transcriptional repressor of direct endogenous target genes in these neurons could not be …
… a transcriptional repressor of direct endogenous target genes in these neurons could not be …
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